Results 61 to 70 of about 661,157 (279)

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

Ethical Precision in Nanoscale Brain Interfacing

Advanced Science, EarlyView.
As brain interfaces approach the nanoscale, precision no longer only measures—it knows, predicts, and potentially reshapes the mind. This work argues that traditional ethics fails under such conditions and proposes a shift toward continuous, operation‐based governance using the recovery–discovery framework to track, constrain, and responsibly steer ...
Guilherme Wood
wiley   +1 more source

Unveiling the Knee Injury Landscape: A Comprehensive Study of Youth Male Football Players in the Central Region of Saudi Arabia

Applied Sciences
Knee injuries represent a significant health concern for young male football players in Saudi Arabia. Despite global research on football-related injuries, there is a distinct lack of studies focusing on this demographic in the Saudi context.
Latifah Almansour, Walaa Sayed Mohammad, Walaa Elsais, Asma Alonazi, Danah Alyahya   +4 more
doaj   +1 more source

Ultrasound‐Activatable Piezoelectric Hydrogel Reprograms Mitochondrial Epigenetics for Osteoarthritis Therapy via the mTOR/GATD3A Axis

Advanced Science, EarlyView.
An ultrasound‐activatable piezoelectric hydrogel reprograms chondrocyte mitochondrial epigenetics via the mTOR/GATD3A axis, clearing damaged mitochondria and alleviating osteoarthritis progression in both mouse models and human cartilage explants. ABSTRACT The avascular nature of cartilage hinders drug delivery for osteoarthritis (OA) therapy.
Hui Zheng, Pengfei Yan, Peng Liu, Chang Yan, Mengqi Zhao, Zuyong Wang, Chao Ma, Rongkai Zhang, Xi Cui, Swee Hin Teoh   +9 more
wiley   +1 more source

Demographics and Injuries Associated With Knee Dislocation: A Prospective Review of 303 Patients

Orthopaedic Journal of Sports Medicine, 2017
Background: Information on the incidence, injury mechanisms, ligament injury patterns, and associated injuries of knee dislocations is lacking in the literature.
Gilbert Moatshe MD, Grant J. Dornan MSc, Sverre Løken MD, PhD, Tom C. Ludvigsen MD, Robert F. LaPrade MD, PhD, Lars Engebretsen MD, PhD   +5 more
doaj   +1 more source

Role of magnetic resonance imaging in the evaluation of the popliteus musclotendinous injuries as a part of the posterolateral corner injuries of the knee

Alexandria Journal of Medicine, 2018
Introduction: The popliteus musclotendinous complex is considered to be one of the main stabilizers of the posterolateral corner of the knee having different attachments and variable sites of injuries, the use of MRI helps the radiologists to depict such
Aly A. Abdel-Kerim Farahat, Abd ElAziz Elnekeidy, Mohamed Abdel Motaleb Abdelgelil   +2 more
doaj   +1 more source

Trauma Mechanisms of Acute Knee injuries in Bouldering and Sport Climbing

Orthopaedic Journal of Sports Medicine, 2020
Background There is limited insight into trauma mechanisms of knee injuries in bouldering and sport climbing for both non-competitive and competitive athletes.
Christoph Lutter MD, Thomas Tischer MD, Prof., Carrie Cooper MD, Luisa Frank, Thilo Hotfiel MD, PD, Robert Lenz MD, Volker Schöffl MD, Prof.   +6 more
doaj   +1 more source

Overuse injuries in the knee, back and hip of top elite female alpine skiers during the off-season preparation period: prevalence, severity and their association with traumatic preinjuries and training load

BMJ Open Sport & Exercise Medicine, 2020
Objectives To investigate knee, back and hip overuse injuries in top female elite alpine skiers during the off-season preparation, which has so far received little attention, and to assess their relationship with traumatic preinjuries and overall ...
Jörg Spörri, Erich Müller, Stefan Fröhlich, Seraina Pazeller, Afsaneh Safar Cherati, Walter O Frey   +5 more
doaj   +1 more source

ROS‐Targeted Nanomotor Therapy in OA: Cartilage Protection and Pain Relief

Advanced Science, EarlyView.
ROS‐responsive NM@MET nanomotors utilize elevated ROS in osteoarthritic joints to promote deep penetration into cartilage and synovium and enable sustained metformin release. By scavenging ROS, regulating NRF2/KEAP1 signaling, protecting chondrocytes, suppressing synovial inflammation, and attenuating nociceptive signaling, NM@MET alleviates pain and ...
Meng Zheng, Changyu Liu, Qin Xia, Arndt F. Schilling, Jiawei Jiang, Renpeng Peng, Zixing Shu, Tian Ma, Danni Luo, Yaoyu Zhang, Yibo Fan, Xuyuan Zhang, Song Li, Kai Wang, Wentao Ke, Yuan Xiong, Yuanli Zhu, Fangzhi Mou, Jun Xiao, Hao Zhu   +19 more
wiley   +1 more source

Ultrasound Detection of Patellar Fracture and Evaluation of the Knee Extensor Mechanism in the Emergency Department

Western Journal of Emergency Medicine, 2016
Traumatic injuries to the knee are common in emergency medicine. Bedside ultrasound (US) has benefits in the rapid initial detection of injuries to the patella.
Kiersten Carter, Arica Nesper, Laleh Gharahbaghian, Philips Perera   +3 more
doaj   +1 more source