Results 111 to 120 of about 369,233 (302)

Leg dominance effects on knee kinematics in unilateral and bilateral squats [PDF]

, 2016
Squatting movements are often used to assess known risk factors of injury such as knee valgus angle. This study aims to investigate the knee kinematics during unilateral and bilateral squats in relation to the dominant and non-dominant leg.
Bridle, C., Moore, J., Mullineaux, D., Mulloy, F.   +3 more
core   +1 more source

Treatment of failed articular cartilage reconstructive procedures of the knee: A systematic review [PDF]

, 2018
Background: Symptomatic articular cartilage lesions of the knee are common and are being treated surgically with increasing frequency. While many studies have reported outcomes following a variety of cartilage restoration procedures, few have ...
Lamplot, Joseph D, Matava, Matthew J, Schafer, Kevin A   +2 more
core   +2 more sources

A Photothermal Transducer Regulates Transmembrane Calcium Flow for Synergistic Osteoarthritis Therapy

Advanced Science, EarlyView.
Upon NIR irradiation at 808 nm, the activity of TRPV4 was inhibited by M2M@BPSC, which led to reduced calcium influx, mitochondrial protection, and, importantly, the transcriptional activation of the STAT6‐EGR2 pathway. The improved macrophage function indirectly readjusts the equilibrium between C‐ECM and F‐ECM to reconstruct a suitable ...
Chenqi Yu, Yang Liu, Kang Kang, Jianfeng Yu, Xiaowei Xia, Yaoge Deng, Yingjie Lu, Huilin Yang, Lisong Li, Wu Xu, Yijian Zhang, Xuesong Zhu   +11 more
wiley   +1 more source

Delayed Surgery, Medial Meniscus Injury, and Younger Age Are All Factors Significantly Associated With High-Grade Knee Laxity Before ACL Reconstruction

Orthopaedic Journal of Sports Medicine
Background: The influence of patient demographics, associated meniscal injuries, and especially the time from injury to surgery on knee laxity before anterior cruciate ligament reconstruction (ACLR) remains insufficiently explored.
Riccardo Cristiani MD, PhD, Eric Hamrin Senorski PT, PhD, Camilo P. Helito MD, PhD, Kristian Samuelsson MD, PhD, Karl Eriksson MD, PhD, Anders Stålman MD, PhD   +5 more
doaj   +1 more source

Running Injuries Due to Strike Patterns [PDF]

, 2017
Running is a very repetitive activity that can lead to surmountable stresses to the body over time that could lead to injury. Running biomechanics can influence the effects that the body will experience.
Rogers, Jamie M
core   +1 more source

Macrophage Extracellular Traps in Immunity and Cancer

Advanced Science, EarlyView.
As a macrophage‐mediated innate defense mechanism, the dysregulated release of METs drives chronic inflammation and influences tumor progression. Furthermore, METs exhibit a functional duality within the tumor microenvironment, capable of both promoting and suppressing tumor development.
Junyao Li, Eugenie Nepovimova, Adam Grundel, Lukas Peter, Qinghua Wu, Kamil Kuca   +5 more
wiley   +1 more source

3D Large‐Scale Subwavelength‐Resolution Sound Sheet Tomography Based on an Active and Programmable Circular Meta‐Array

Advanced Science, EarlyView.
A programmable 2048‐element circular ultrasound array combined with a compact acoustic lens produces a thin “sound sheet” over a large field of view, and records echoes with wide angular diversity across the ring aperture. Coherence‐enhanced beamforming converts full‐matrix data into high‐contrast tomographic slices, delivering near‐diffraction‐limited
Qiu‐De Zhang, Zi‐Bin Lin, Zhuo Chen, Zhao‐Hui Liu, Jin‐Lian He, Jun‐Jie Song, Long‐Sheng Zeng, Liang Zhou, Ming‐Yue Ding, Yu‐Gui Peng, Ming Yuchi, Xue‐Feng Zhu   +11 more
wiley   +1 more source

Age, Workload, and Usage Rate: Risk Factors Associated With Knee Injuries in Women’s National Basketball Association Athletes

Orthopaedic Journal of Sports Medicine
Background: Knee injuries are among the most common injuries in female basketball players. Despite the growing popularity of professional women's basketball, particularly the Women's National Basketball Association (WNBA), there are limited recent data ...
Sanjit Menon BS, Skanda Sai BS, John Traversone MD, Eugenia Lin MD, Sailesh V. Tummala MD, Anikar Chhabra MD, MBA   +5 more
doaj   +1 more source

Inhibiting cGAS‐STING to Preserve Mitochondrial–Nuclear Communication and Stemness in Young Tendon Stem Cells: A Hydrogel Strategy against Age‐Related Tendinopathy

Advanced Science, EarlyView.
A dual‐targeting strategy to rejuvenate aged tendons. A reactive oxygen species (ROS)‐responsive hydrogel co‐delivers a selenium nanozyme (scavenges ROS) and a STING inhibitor to tendon stem cells. This combined action restores mitochondria–nucleus communication, alleviates cellular senescence, and rejuvenates tendon regeneration, offering a novel ...
Zhuo Zhang, Weiyong Song, Heng Yin, Yi Wang, Yi Zou, Yuling Li, Yue Luo, Chao Xiang, Xiaoqin Liu, Yan Xiong, Yong Wang, Ke Jiang   +11 more
wiley   +1 more source

Beyond Extracellular Vesicle (EV) Hype: Practical Solutions and Remaining Hurdles in EV Research, Manufacturing, and Clinical Translation

Advanced Science, EarlyView.
ABSTRACT Extracellular vesicles (EVs) are nanoscale mediators of intercellular communication with diverse molecular cargoes that reflect their cell of origin. Advances in isolation, detection, and single‐particle analytics have revealed increasing molecular and functional heterogeneity, while exposing limitations in how EV identity and activity are ...
David J. Lundy, Zoe L. Chau, Sheng‐You Chen, Nanami Fujisawa, John J. Hill, Barnett M. Hsu, Joanne K. Liu, Karol W. Mai, James J. Lai   +8 more
wiley   +1 more source