Results 91 to 100 of about 3,037,337 (268)

Long‐Term Expandable Periosteal Organoids Reconstruct a Functional Regenerative Niche That Support Hematopoietic Stem Cell Maintenance and Bone Repair

Advanced Science, EarlyView.
A robust periosteal organoid system enables long‐term expansion while preserving native cellular heterogeneity. These organoids recapitulate functional niche environments, support hematopoietic stem cell maintenance, and attenuate aging‐associated decline ex vivo.
Jia Qing, Lanxin Gu, Lipeng Fu, Xin Gao, Zechuan Li, Hui Zhang, Wenpeng Song, Huixin Lv, Yongsheng Zhou, Ping Zhang   +9 more
wiley   +1 more source

Influence of Prophylactic Ankle Bracing on Knee Joint Moments and Ground Reaction Forces during Side-step Cutting Tasks [PDF]

The Asian Journal of Kinesiology
OBJECTIVES Prophylactic ankle bracing is widely used to prevent ankle sprains, but its effects on knee joint mechanics, particularly regarding ACL injury risk, are less understood.
Hyung Suk Yang, Rhonda Boros, Nida Roncesvalles, Yoonjung Park   +3 more
doaj   +1 more source

Pure Varus Injury to the Knee Joint

Clinics in Orthopedic Surgery, 2015
A 30-year-old male was involved in a car accident. Radiographs revealed a depressed marginal fracture of the medial tibial plateau and an avulsion fracture of the fibular head. Magnetic resonance imaging showed avulsion fracture of Gerdy's tubercle, injury to the posterior cruciate ligament (PCL), posterior horn of the medial meniscus, and the ...
Yoo, Jae Ho, Lee, Jung Ha, Chang, Chong Bum   +2 more
openaire   +2 more sources

Astrocytic Ketogenesis Protects Central Nervous System Injury via CPT1A Stabilization and Epigenetic Regulation

Advanced Science, EarlyView.
A distinct astrocyte subpopulation, enriched at the lesion border, drives CNS repair through enhanced ketone body metabolism. This process promotes neuronal survival and axonal sparing via CPT1A stabilization and H3K9bhb‐dependent epigenetic reprogramming, positioning astrocytic ketogenesis as a promising therapeutic target for tissue regeneration ...
Dishui Pan, Haoming Shu, Rui Gao, Yilong Ren, Wu Ye, Xuhui Ge, Yao Gu, Yufeng Zhu, Xiaokun Wang, Honglin Teng, Xuhui Zhou, Wei Liu, Yang Gao, Jianquan Zhao, Weihua Cai   +14 more
wiley   +1 more source

Biomechanical analysis of hip-knee joint impact injury in typical postures

BMC Musculoskeletal Disorders
Objective Hip and knee soft tissues are susceptible to different forms of impact injury risk in typical postures, the biomechanical mechanism of hip-knee joint impact injury is not clear yet.
Song Li, Qiang Li, Ao Shen, Tingqiang Yao   +3 more
doaj   +1 more source

Revision rates after primary hip and knee replacement in England between 2003 and 2006 [PDF]

, 2008
<b>Background</b>: Hip and knee replacement are some of the most frequently performed surgical procedures in the world. Resurfacing of the hip and unicondylar knee replacement are increasingly being used.
Boroff, Mick, Pickford, M., Borroff, Mick, Keith Tucker, Tucker, K., MacGregor, Alex J., on behalf of the Steering Committee of the National Joint Regist, Macgregor, AJ, Copley, LP, Lynn P Copley, Lewsey, J.D., Pickford, M, Copley Lynn P, Lewsey, Jim D., Tucker, K, Copley, Lynn P, Borroff, M, Lewsey, JD, Gregg, Paul, Gregg, P, Pickford Martin, van der Meulen, JH, Porter, Martyn, Sibanda, N, Lewsey Jim D, Copley, L.P., Mick Borroff, Paul Gregg, Porter, M, Copley, Lynn P., Porter Martyn, Martyn Porter, Jan H van der Meulen, Sibanda Nokuthaba, Gregg Paul, MacGregor, A.J., Alex J MacGregor, Borroff Mick, van der Meulen, J.H., Steering Committee of the National Joint Registry (NJR) for England and Wales, Sibanda, Nokuthaba, MacGregor, Alex J, Tucker Keith, Pickford, Martin, Tucker, Keith, Nokuthaba Sibanda, Sibanda, N., van der Meulen, Jan H, Steering Committee of the National Joint Registry (NJR) for Engl, MacGregor Alex J, Porter, M., Gregg, P., van der Meulen, Jan H., Borroff, M., Martin Pickford, van der Meulen Jan H, Lewsey, Jim D, Jim D Lewsey   +57 more
core   +2 more sources

A Programmable Braided Silk‐Glass Fiber Ligament Promoting Rapid Motoric Recovery

Advanced Science, EarlyView.
A scalable three‐dimensional braiding strategy integrates silk and glass fibers into customizable artificial ligaments with programmable “J‐shaped” nonlinear mechanics. The silk‐rich architecture supports osseoligamentous integration, while glass fibers provide mechanical reinforcement and biomimetic mineralization cues, enabling strain‐adaptive load ...
Changbo Lu, Daming Liu, Haoxin Zhang, Zhiwei Qiao, Qiuming Gao, Jia Meng, Hongyin Yue, Songkai Li, Shuo Zhang, Tao Yuan, Yun Xue, Hui Jiang, Zhenguo Liu, Yibo Wang, Nirong Bao, Yuli Chen, Xiaojiang Yang   +16 more
wiley   +1 more source

Continuous time series analysis on the effects of induced running fatigue on leg symmetry using kinematics and kinetic variables: Implications for knee joint injury during a countermovement jump. [PDF]

Front Physiol, 2022
Gao Z, Zhao L, Fekete G, Katona G, Baker JS, Gu Y.   +5 more
europepmc   +1 more source

A Multi‐Structural Radiomic Digital Phenotyping Framework for Deciphering Preclinical Evolution of Degenerative Meniscal Tears

Advanced Science, EarlyView.
Subclinical matrix disruption precedes degenerative meniscal tears across the knee joint. A spatial compartmental radiomics model utilizing 3D‐DESS MRI captures early osteochondral destabilization, accurately predicting incident tears up to four years pre‐collapse. Feature attributions uncover coordinated chondral and osseous alterations, advancing non‐
Shengfa Li, Hao Liu, Yanbin Zhu, Hang Zhang, Qifeng Tao, Wenbo Zhao, Xin Miao, Shanshan Yang, Tianyu Chen, David Hunter, Changhai Ding, Ting Wang, Juan Wang, Wei Chen   +13 more
wiley   +1 more source

Reln mRNA Delivery Drives Neurogenic Bone Regeneration by Orchestrating Schwann Cell‐Mediated Exosomal Trafficking

Advanced Science, EarlyView.
MSNs serve as a robust vehicle for CRISPRa‐mediated Reln induction, driving bone repair through the establishment of a neurogenic‐supportive microenvironment. ABSTRACT Neurogenic bone regeneration is essential for the effective restoration of bone tissue functionality, while the mechanisms and new strategies underlying neurogenic bone regeneration ...
Shuai Lin, Qianwen Li, Duo Liu, Mingzhao Li, Han Zhang, Liujing Chen, Yan Yu, Jiuhui Jiang, Chun Xu, Ruili Yang   +9 more
wiley   +1 more source