Results 131 to 140 of about 35,004 (295)

The KineSpring® Knee Implant System: an implantable joint-unloading prosthesis for treatment of medial knee osteoarthritis

, 2013
Anton G Clifford,1 Stefan M Gabriel,1 Mary O’Connell,1 David Lowe,1 Larry E Miller,2,3 Jon E Block31Moximed, Inc, Hayward, CA, USA; 2Miller Scientific Consulting, Inc, Arden, NC, USA; 3The Jon Block Group, San Francisco, CA, USAAbstract ...
Miller LE, Lowe D, O’ Connell M, Block JE, Gabriel SM, Clifford AG   +5 more
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The effect of tourniquet use on fixation quality in cemented total knee arthroplasty a prospective randomized clinical controlled RSA trial

, 2014
A concern that arises with any change in technique is whether it affects the long-term implant stability. The objective of this study was to evaluate the early migration, measured by radiostereometric analysis (RSA), and the functional outcome of the ...
Toksvig-Larsen, Sören,, Harsten, Andreas,, Molt, Mats,, Lund University.   +3 more
core   +1 more source

Osteoarthritis: An Immuno‐Inflammatory Disease‐Mechanisms of Immune Cell Dysregulation and Potential Therapeutic Strategies

Med Research, EarlyView.
This review summarizes the immuno‐inflammatory mechanisms driving the pathogenesis of osteoarthritis (OA), extending beyond the traditional view of OA as a purely degenerative disease to incorporate immune cell infiltration, inflammatory factor release, and the formation of a chronic low‐grade inflammatory microenvironment.
Qingqiang Lei, Xiaoxian Lou, Xu Su, Shubao Liu, Yanli Tong, Jie Chen, Xuerui Chen, Wenjun Mao, Hui Yu, Liangbin Lin   +9 more
wiley   +1 more source

Enhanced pre-clinical assessment of total knee replacement using computational modelling with experimental corroboration & probabilistic applications

, 2009
Demand for Total Knee Replacement (TKR) surgery is high and rising; not just in numbers of procedures, but in the diversity of patient demographics and increase of expectations.
Strickland, Anthony Michael
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History of Total Knee Replacement [PDF]

, 2010
Hinge arthroplasty was first introduced over 100 years ago, and it has been refined over the years through a succession of increasingly complex designs that have led to the present rotating hinge prosthesis.
양익환
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Cosmetic effect of knee joint in a knee disarticulation prosthesis

, 2014
Despite numerous advantages, knee disarticulations (KDs) are rarely performed because of the anticipated KD prosthesis fitting problems that include the positioning of the knee joint distally from the KD socket.
Roorda, Leo D., van Kuijk, Annette A., Geertzen, Jan H.; id_orcid, Geertzen, Jan H., de laat, Fred A., van der Pluijm, Mark J.   +5 more
core   +1 more source

SURMOUNT‐REAL UK: A Pragmatic Randomized Clinical Trial to Assess the Effectiveness of Tirzepatide in Adults With Obesity

Obesity, EarlyView.
ABSTRACT Objective SURMOUNT‐REAL UK will evaluate the effectiveness of tirzepatide when offered in addition to standard‐of‐care (SoC) in adults with Class I obesity (BMI ≥ 30 and ≤ 34.9 kg/m2) and without diabetes in a UK primary care setting. Methods A 5‐year, phase 4, multicenter, open‐label, pragmatic randomized clinical trial is enabled through ...
Martin K. Rutter, Julie Mount, J. Martin Gibson, Joanne Webb, Cheryl Marler, Catherine Reed, Mugdha Gore, Wenyu Ye, Elisa Gomez Valderas, John Wilding, Naveed Sattar, Melanie J. Davies, Kamlesh Khunti, Richard Haynes, Rachel L. Batterham   +14 more
wiley   +1 more source

Instrumented Prosthesis for Knee Implants Monitoring

In this work we present an instrumented smart knee prosthesis for in-vivo measurement of forces and kinematics. Studying the constraints, we designed minimal sensory systems to be placed in the polyethylene part of the prosthesis.
Bertsch, Arnaud, Renaud, Philippe, Leclercq, Vincent, Meurville, Eric, Dejnabadi, Hooman, Simoncini, Matteo, Dehollain, Catherine, Jolles-Haeberli, Brigitte, Farine, Pierre-André, Hasenkamp Carreira, Willyan, Ryser, Peter, Tanner, Steve, Ali, Shafqat, Aminian, Kamiar, Arami, Arash, Atasoy, Oguz   +15 more
core   +1 more source

Mesenchymal stromal cell therapy for rheumatoid arthritis: Long‐term efficacy, safety, and mechanistic insights

Rheumatology &Autoimmunity, EarlyView.
Graphical abstract summarizing the multifactorial pathogenesis of rheumatoid arthritis (RA) and the therapeutic potential of mesenchymal stromal cell (MSC) therapy. MSCs provide promising benefits through their immunomodulatory properties, low immunogenicity, ability to promote tissue repair, and multi‐lineage differentiation, presenting a potential ...
Yingjia Chen, Ruiyu Gao, Xing Guo, Genhong Yao, Xiaojun Tang, Yile E. Liu, Lingyun Sun   +6 more
wiley   +1 more source

Load applied on a bone-anchored transfemoral prosthesis: characterisation of a prosthesis : a pilot study

, 2013
The objectives of this study were (A) to record the inner prosthesis loading during activities of daily living (ADL), (B) to present a set of variables comparing loading data, and (C) to provide an example of characterisation of two prostheses.
Branemark, Rickard, Frossard, Laurent A., Hagberg, Kerstin, Haggstrom, Eva   +3 more
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