Results 101 to 110 of about 872,819 (289)

Physics‐Constrained Constitutive Learning of Rate‐Limiting Timescales for Efficient Hydrogen‐Based Direct Reduction for Green Steel Making

Advanced Science, EarlyView.
A conversion‐resolved constitutive framework is developed for the hydrogen‐based direct reduction of iron oxide pellets. Effective reaction and transport timescales are inferred directly from measured trajectories and mapped against operating conditions, pellet architecture, and composition. The analysis reveals how late‐stage transport control emerges
Anurag Bajpai, Barak Ratzker, Pasquale Cavaliere, Dierk Raabe   +3 more
wiley   +1 more source

Statistical analysis plan for the Robotic-Assisted Surgery and Kinematic ALignment in total knee arthroplasty (RASKAL) registry-nested randomized trial

Bone & Joint Open
Aims: There is uncertainty over whether robotic-assisted surgery (RAS) or kinematic alignment (KA) improves outcomes in total knee arthroplasty (TKA).
Samuel J. MacDessi, Gregory C. Wernecke, Durga Bastiras, Khashayar Ghadirinejad, Dylan Harries, Kara Cashman, Emma Heath, Michelle Lorimer, Carl Holder, Ian A. Harris   +9 more
doaj   +1 more source

Physics‐Informed Machine Learning for Sustainable Alloy Design: Toward a Recyclable Unified Q&P Steel

Advanced Science, EarlyView.
A physics‐informed property‐bridging framework links high‐throughput hardness screening to tensile performance in quenching and partitioning steels. By transferring metallurgically guided representations across properties, a single alloy composition is designed to achieve multiple strength grades through heat‐treatment tuning alone, offering a ...
Xiaolu Wei, Yong Li, Chenchong Wang, Lingyu Wang, Xiang Song, Keming Mao, Yu Zhang, Wei Xu   +7 more
wiley   +1 more source

Ultrasound‐Activatable Piezoelectric Hydrogel Reprograms Mitochondrial Epigenetics for Osteoarthritis Therapy via the mTOR/GATD3A Axis

Advanced Science, EarlyView.
An ultrasound‐activatable piezoelectric hydrogel reprograms chondrocyte mitochondrial epigenetics via the mTOR/GATD3A axis, clearing damaged mitochondria and alleviating osteoarthritis progression in both mouse models and human cartilage explants. ABSTRACT The avascular nature of cartilage hinders drug delivery for osteoarthritis (OA) therapy.
Hui Zheng, Pengfei Yan, Peng Liu, Chang Yan, Mengqi Zhao, Zuyong Wang, Chao Ma, Rongkai Zhang, Xi Cui, Swee Hin Teoh   +9 more
wiley   +1 more source

Unintentional Valgus Malalignment in Mechanically Aligned Total Knee Arthroplasty Leads to Higher Prosthetic Failure Rates. A National Registry Survivorship Analysis of Coronal, Sagittal and Rotational Alignment Using Computed Tomography

Orthopaedic Journal of Sports Medicine
Objective: Unlike coronal malalignment, little is known about whether sagittal and rotational malalignment increases failure rates in mechanically aligned (MA) total knee arthroplasty (TKA).
Samuel MacDessi MBBS (Hons) FRACS PhD, Luke Corban BMedSc BSc(Hons), Jil Wood MSN, Michael McAuliffe, Darren Chen MBBS (Hons) FRACS   +4 more
doaj   +1 more source

A Monolithic Janus Hydrogel Pressure Sensor for Wearable Motion and Physiological Monitoring

Advanced Science, EarlyView.
This work reports a monolithic Janus hydrogel pressure sensor featuring integrated conductive PEDOT and insulating PEGDA layers. The fabricated device achieves a rapid response time, a wide operating range, and good cyclic durability. The sensor demonstrates robust performance in tracking dynamic human joint motions, offering a scalable strategy for ...
Syed Atif Ali, Zeeshan Alam Ansari, Reynaldo Carlos Kuizon Montalbo, Hailemichael Ayalew, Yu‐Sheng Hsiao, Chih‐Wei Chu, Hsiao‐hua Yu, Hsiung‐Lin Tu   +7 more
wiley   +1 more source

Inverse Design of Pre‐Strain via a Predictive Electromechanical Model for Enhanced Strain Sensing

Advanced Science, EarlyView.
An analytical electromechanical model rooted in microcrack evolution mechanics is globally calibrated from only eight pre‐strain datasets, enabling prediction of the complete sensing response at untested pre‐strain values within the calibrated design space (R2 > 0.99).
Jia‐Chen Shang, Rui Wang, Bo Lu, Ming‐Liang Song, Yu‐Yi Chen, Kuo Han, Xin‐Jie Feng, Bin Sun, Yao‐Guang Cao, Xiao‐Yu Yan, Shi‐Chun Yang   +10 more
wiley   +1 more source

A clinical decision-making algorithm for posterolateral corner injuries of the knee: Development and internal validationWhat are the new findings?

Journal of ISAKOS
Purpose: Posterolateral corner (PLC) injuries of the knee remain a complex and heterogeneous clinical entity, with substantial variability in surgical management and no widely accepted criteria to guide treatment selection.
Horacio Rivarola, MD, Cristian Collazo, MD, Marcos Palanconi, MD, Marcos Meninato, MD, Carlos Peñaherrera-Carrillo, MD, Alejandro Barros Castro, MD, Francisco Endara Urresta, MD   +6 more
doaj   +1 more source

A Decoy‐Receptor‐Armed Biomimetic Nanotherapeutic With Inherent Tropism for Conserved Pathogenic Macrophages for Treating Osteoarthritis and Intervertebral Disc Degeneration

Advanced Science, EarlyView.
A biomimetic doppelgänger nanosystem neutralizes extracellular inflammatory cytokines and silences intracellular pyroptosis, reprogramming pathogenic macrophages to attenuate both joint and spine degeneration. ABSTRACT Osteoarthritis (OA) and intervertebral disc degeneration (IVDD) are debilitating musculoskeletal disorders driven by shared ...
Fudong Li, Bin Zhang, Zhiqiu Zhang, Bing Zheng, Linhui Han, Chen Yan, Jialin Li, Kaiqiang Sun, Tianyi Zhao, Jiangang Shi   +9 more
wiley   +1 more source

PREDICTION OF FEAR FACTORS BEFORE TOTAL KNEE REPLACEMENT: A MIXED METHOD ANALYSIS ON ADVANCED KNEE OSTEOARTHRITIS PATIENTS

Pakistan Armed Forces Medical Journal, 2020
Objective: To determine fear factors before total knee replacement in advanced knee osteoarthritis patients. Study Design: Mixed method study. Place and Duration of Study: Study was conducted at department of Orthopedics, Pakistan Ordinance ...
Muhammad Ikram, Sadia Ijaz, Munawer Latif Memon, Syed kamran Muhammad Shah, Sajid Ejaz Rao   +4 more
doaj   +4 more sources