Results 91 to 100 of about 872,819 (289)

Outcome improvement for anaemia and iron deficiency in ERAS hip and knee arthroplasty: a descriptive analysis

Perioperative Medicine
Background and purpose Preoperative anaemia including iron deficiency anaemia (IDA) is a well-established perioperative risk factor. However, most studies on iron therapy to treat IDA have been negative and few have been conducted within an enhanced ...
Christoffer Calov Jørgensen, Henrik Kehlet, The Center for Fast-track Hip, Knee Replacement Collaborative Group   +2 more
doaj   +1 more source

Combating Inflammation and Promoting Anabolism in Osteoarthritic Cartilage Defect With an MMP13‐Sensing Dual‐Drug Scaffold

Advanced Science, EarlyView.
ABSTRACT Osteoarthritis (OA) is a widespread degenerative joint condition marked by progressive cartilage breakdown, and a chronic inflammatory microenvironment, where conventional therapies largely fail to halt disease progression. To address this unmet need, an intra‐articularly implantable, disease‐responsive scaffold was developed for combinatorial
Zhen Zhang, Bangheng Liu, Yulei Mu, Huiqun Zhou, Liang Ma, Chenjie Xu, Dong‐An Wang   +6 more
wiley   +1 more source

Standardising the clinical assessment of coronal knee laxity [PDF]

, 2012
Clinical laxity tests are used for assessing knee ligament injuries and for soft tissue balancing in total knee arthroplasty. This study reports the development and validation of a quantitative technique of assessing collateral knee laxity through ...
Riches, Philip E., Clarke, Jon V., Wearing, Scott C., Deakin, Angela H., Wilson, William T., Picard, Frederic   +5 more
core   +1 more source

Use of Topical (Intra-articular) Tranexamic Acid to Minimise Blood Loss and Transfusion in Total Knee Replacement Surgery [PDF]

, 2010
Introduction Total knee replacement (TKR) is a common orthopaedic procedure, with 20-70% of patients needing 1-3 units of blood, although allogeneic transfusion is not risk free.
ALSHRYDA, SATTAR,JABER,MOHR, Alshryda, Sattar Jaber Mohr   +1 more
core  

Ethical Precision in Nanoscale Brain Interfacing

Advanced Science, EarlyView.
As brain interfaces approach the nanoscale, precision no longer only measures—it knows, predicts, and potentially reshapes the mind. This work argues that traditional ethics fails under such conditions and proposes a shift toward continuous, operation‐based governance using the recovery–discovery framework to track, constrain, and responsibly steer ...
Guilherme Wood
wiley   +1 more source

Association of preoperative psychopharmacological treatment and the risk of new chronic opioid use after hip and knee arthroplasty: a Danish registry-based cohort study of 73,033 procedures

Acta Orthopaedica
Background and purpose: Chronic opioid use is of great concern worldwide. Thus, identification of risk factors for new chronic opioid use (COU) after hip and knee arthroplasty is imperative to target preventive strategies. Depression/anxiety may be risk
Simon Kornvig, Henrik Kehlet, Christoffer C Jørgensen, Anders Fink-Jensen, Poul Videbech, Alma B Pedersen, Claus Varnum   +6 more
doaj   +1 more source

Joint loading asymmetries in knee replacement patients observed both pre- and six months post-operation

BackgroundStudies have highlighted asymmetries in knee joint moments during activities of daily living in individuals with osteoarthritis and joint replacements.
Stokes, M., Taylor, M., Worsley, Peter, Barrett, D.S.   +3 more
core   +1 more source

Referral recommendations for osteoarthritis of the knee incorporating patients' preferences [PDF]

, 2010
Background. GPs have to respond to conflicting policy developments. As gatekeeper they are supposed to manage the growing demand for specialist services and as patient advocate they should be responsive to patients' preferences.
McCaskie, Andrew W, Musila, Nyokabi, Nyokabi Musila, McCaskie, A. W., Andrew W McCaskie, Musila, N., van der Meulen, Jan H, Meulen, J. H. van der, Jan H van der Meulen, Nick Black, Underwood, Martin, Martin Underwood, Aileen Clarke, Black, Nick, Black, N., Clarke, Aileen   +15 more
core   +1 more source

Sustainable Materials Design With Multi‐Modal Artificial Intelligence

Advanced Science, EarlyView.
Critical mineral scarcity, high embodied carbon, and persistent pollution from materials processing intensify the need for sustainable materials design. This review frames the problem as multi‐objective optimization under heterogeneous, high‐dimensional evidence and highlights multi‐modal AI as an enabling pathway.
Tianyi Xu, Tianshuo Wei, Yan Ge, Bo Peng, Yue Li, Maolin Wang, Peng Wen, Chao Yang, Ye Wei   +8 more
wiley   +1 more source

History of Total Knee Replacement [PDF]

, 2010
Hinge arthroplasty was first introduced over 100 years ago, and it has been refined over the years through a succession of increasingly complex designs that have led to the present rotating hinge prosthesis.
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