Results 71 to 80 of about 83,783 (313)

A Synovium‐on‐Chip Platform to Study Multicellular Interactions in Arthritis

Advanced Healthcare Materials, EarlyView.
The Synovium‐on‐Chip comprises a thin microporous PDMS membrane to support co‐culture of fibroblast‐like synoviocytes (FLS), THP‐1‐derived macrophages, and endothelial cells, enabling real‐time analysis of synovial‐vascular interactions. FLS migration through the pores drives endothelial remodeling, while TNF‐α stimulation induces robust inflammatory ...
Laurens R. Spoelstra, Fleur R. Semmekrot, Nuno Araújo‐Gomes, Daniël Wijnperle, Monique M. A. Helsen, Martijn H.J. Van Den Bosch, Loes. I. Segerink, Séverine Le Gac, Marcel Karperien   +8 more
wiley   +1 more source

Start, Stop, Rewind, Repeat—Cyclic Exposure of Adipose Stromal Cells‐derived Cartilage Organoids to Chondrogenic and Proliferative Cues to Achieve Scaled‐up and Customizable Bone Formation by Endochondral Ossification

Advanced Healthcare Materials, EarlyView.
This study exploits the plasticity of ASCs‐derived cartilage organoids which generate a perichondrial layer of MSCs when exposed to cyclic chondrogenic/proliferative cues. Using these organoids as building blocks, we develop (i) Phalange Shaped Tissue Engineered Cartilage (Pa‐TECs), recapitulating endochondral ossification suitable for the treatment of
Pablo Pfister, Emilien Lhospice, Andrés García‐García, Robert Paillaud, Sebastian Jung, Romain Schaller, Elisabeth A. Kappos, Claude Jaquiéry, Tarek Ismail, Dirk J. Schaefer, Michael de Wild, Ivan Martin, Alexandre Kaempfen, Arnaud Scherberich, Adrien Moya   +14 more
wiley   +1 more source

Statistical analysis plan for the Robotic-Assisted Surgery and Kinematic ALignment in total knee arthroplasty (RASKAL) registry-nested randomized trial

Bone & Joint Open
Aims: There is uncertainty over whether robotic-assisted surgery (RAS) or kinematic alignment (KA) improves outcomes in total knee arthroplasty (TKA).
Samuel J. MacDessi, Gregory C. Wernecke, Durga Bastiras, Khashayar Ghadirinejad, Dylan Harries, Kara Cashman, Emma Heath, Michelle Lorimer, Carl Holder, Ian A. Harris   +9 more
doaj   +1 more source

Medical Fabrics with Non‐Antibiotic, Supramolecular Antimicrobial Coatings: A Preventive Approach to Combat Biofilm Formation and Bacterial Dissemination

Advanced Healthcare Materials, EarlyView.
The study presents an antibiotic‐free strategy using medical fabrics coated with supramolecular assemblies of polyarginine and hyaluronic acid. These coatings showed strong antimicrobial and anti‐biofilm activity in vitro and in vivo, achieving major bacterial load reductions, including against MRSA.
Adjara Diarrassouba, Abdessalem Rekiki, Cécile Loubière, Sabine Kuchler‐Bopp, Lauriane Petit, Cynthia Calligaro, Derry Mercer, Aurore Gaudin, Naomi Canourgues, Emilie Adicéam, Benoit Beitz, Jeremy Welsch, Annabelle Vigué, Markus j. Kettel, Michael Karl, Chloé Guilbaud‐Chéreau, Philippe Lavalle, Nihal Engin Vrana, Skander Hathroubi   +18 more
wiley   +1 more source

CLINICAL EVALUATION OF POST TOTAL HIP / KNEE REPLACEMENT IN HIP / KNEE SPINE SYNDROME

Journal Orthopaedi and Traumatology Surabaya, 2017
Insiden osteoarthritis pada hip joint, osteoarthritis pada knee joint, dan degenerative lumbar spondylosis semakin meningkat seiring dengan bertambahnya populasi penduduk usia tua. Kasus Hip/Knee Spine syndrome sendiri cukup sering ditemukan.
Achmad Fachrizal, Komang Agung Irianto
doaj   +1 more source

Allergic Dermatitis Following Bilateral Oxidized Zirconium Total Knee Replacements

, 2021
Marlon M Mencia, Shamir O Cawich
openalex   +1 more source

Sculpting the Future of Bone: The Evolution of Absorbable Materials in Orthopedics

Advanced Materials, EarlyView.
This review summarizes the current status of polymeric, ceramic, and metallic absorbable materials in orthopedic applications, and highlights several innovative strategies designed to enhance mechanical performance, control degradation, and promote bioactivity. We also discuss the progress and translational potential of absorbable materials in treating
Zhao Wang, Zehui Lv, Xuejie Cai, Yingjie Wang, Bo Peng, Haojing Xu, Hualuo Pang, Xingdong Yang, Jiawei Xu, Yixin Bian, Bin Feng, Peng Wen, Yufeng Zheng, Xisheng Weng   +13 more
wiley   +1 more source

Stable occurrence of knee and hip total joint replacement in Central Finland between 1986 and 2003: an indication of improved long-term outcomes of rheumatoid arthritis [PDF]

, 2006
Tuulikki Sokka, H. Kautiainen, Pekka Hannonen   +2 more
openalex   +1 more source

Materials and System Design for Self‐Decision Bioelectronic Systems

Advanced Materials, EarlyView.
This review highlights how self‐decision bioelectronic systems integrate sensing, computation, and therapy into autonomous, closed‐loop platforms that continuously monitor and treat diseases, marking a major step toward intelligent, self‐regulating healthcare technologies.
Qiankun Zeng, Hong Liu, Yongheng Zhang, Youbin Zheng, Xuyin Ding, Mengni Zhu, Guoyue Shi, Yan Wang, Hossam Haick, Min Zhang   +9 more
wiley   +1 more source

Unicompartmental knee replacement - An Underrated Alternative of Total Knee Replacement: A Matched Comparative Study Analysing Their Benefits and Risks in Local Population

Journal of Orthopaedics, Trauma and Rehabilitation, 2018
Introduction The demand of knee arthroplasty is increasing worldwide with aging population. Even though unicompartmental knee replacement is associated with fewer complications namely stroke, myocardial infarction, thrombo-embolism, blood transfusion and
Tarn Karson, Lee Qun-Jid, Wong Yiu-Chung
doaj   +1 more source