Results 221 to 230 of about 370,892 (284)

Long-Term Clinical Impact of Radiographic Patellofemoral Osteoarthritis After Sulcus-Deepening Trochleoplasty: A Retrospective Cohort Study. [PDF]

Orthop J Sports Med
Pineda T, Guarino A, Cance N, Dan MJ, Mazy D, Demey G, Dejour DH.   +6 more
europepmc   +1 more source

Electrical Impedance Myography Detects Disease Progression over 12 to 24 Months in Facioscapulohumeral Muscular Dystrophy

Annals of Neurology, EarlyView.
Objective Targeted therapies for facioscapulohumeral muscular dystrophy (FSHD) are progressing through clinical trials. Electrical impedance myography (EIM) provides a noninvasive biomarker of muscle composition that may be valuable especially in early phase trials. This study evaluated EIM data from a multicenter FSHD cohort over 24 months.
Karlien Mul, Michael P. McDermott, Russell J. Butterfield, Bakri Elsheikh, Kate Eichinger, Nicholas E. Johnson, Doris G. Leung, Samantha LoRusso, Leann Lewis, William B. Martens, Perry B. Shieh, Leo H. Wang, Michaela Walker, Rabi Tawil, Jeffrey M. Statland, ReSolve Investigators of the FSHD‐CTRN   +15 more
wiley   +1 more source

Correlations Between Osteocyte Lacuno‐Canalicular Network and Material Characteristics in Healthy and Mechanically Stimulated Murine Tibiae

Advanced NanoBiomed Research, EarlyView.
This article reveals how calcium content, mineral nanostructure, and lacuno‐canalicular network (LCN) organization interact to shape bone heterogeneity in mouse tibiae. Advanced multimodal imaging uncovers that mechanical loading promotes mature mineral structures even in low‐calcium regions, highlighting LCN‐driven mineralization and offering new ...
Victoria Schemenz, Maximilian Rummler, Alexander van Tol, Isabela Vitienes, Tobias Thiele, Markus A. Hartmann, Manfred Burghammer, Peter Fratzl, Richard Weinkamer, Bettina M. Willie, Wolfgang Wagermaier   +10 more
wiley   +1 more source

Preserved Efficacy of Intra-articular Autologous Protein Solution in Patients Aged Over 80 Years With Knee Osteoarthritis: A Comparison With Younger Counterparts. [PDF]

Cureus
Kaneko Y, Hayakawa K, Nojiri S, Niki Y, Fujita N.   +4 more
europepmc   +1 more source

Decoding the Pathophysiology of Autoimmune Diseases—Mechanism, Triggers, and Nanotherapeutics: A Review

Advanced NanoBiomed Research, EarlyView.
This review highlights how autoimmune diseases arise from intertwined immunological, genetic, and environmental factors, emphasizing gut microbiota dysbiosis as a pivotal driver. It outlines emerging nanotechnology‐based strategies—such as liposomes, hydrogels, and polymeric nanoparticles—that enhance targeted drug delivery, minimize systemic toxicity,
Md. Meraj Ansari, Yunhui Min, Eun‐Ju Ko, Doyoung Kwon, Rehan Khan, Young‐Ok Son   +5 more
wiley   +1 more source

Clinical validation of fully automated (peri-)articular tissue analysis for assessing osteoarthritis progression: A narrative review. [PDF]

Osteoarthr Cartil Open
Wirth W, Eder J.
europepmc   +1 more source

Multimaterial Triphasic Scaffold Replicates Enthesis Microenvironment to Modulate Early Cell Responses

Advanced NanoBiomed Research, EarlyView.
A bioinspired triphasic scaffold integrating 3D printed polycaprolactone and electrospun poly(lactic‐co‐glycolic acid) is developed to replicate the organization of the tendon‐to‐bone enthesis. Cyclic mechanical stimulation induces spatially defined cell morphology and lineage‐related gene expression in human mesenchymal stem cells, highlighting the ...
Ginevra Pegollo, Simone Micalizzi, Girish Pattappa, Philipp Stahlhut, Jürgen Groll, Carmelo De Maria, Denitsa Docheva, Giovanni Vozzi   +7 more
wiley   +1 more source

Short-term Outcomes of Unrestricted Kinematic Alignment: Total Knee Arthroplasty With a Medial Pivot Implant: A Japanese Multicenter Study. [PDF]

Arthroplast Today
Nakamura M, Soda Y, Yamamoto T, Fukushima S, Hayashi T, Sugimoto K, Satake S, Nakagawa S, Michishita K.   +8 more
europepmc   +1 more source

Distal femoral morphology as a risk factor for osteoarthritis

The Anatomical Record, EarlyView.
Abstract Osteoarthritis (OA) is a leading cause of disability affecting millions of adults in the United States, commonly resulting in the need for total knee arthroplasty (TKA) to restore mobility and quality of life. This study investigates potential differences in baseline distal femoral shape between individuals who received TKA due to OA and a ...
Haley Horbaly
wiley   +1 more source

Automated deep-learning quantification of nine patellofemoral instability parameters on multislice CT images : development and validation of the GU2Net model. [PDF]

Bone Jt Open
Ye Q, Ying Y, Hua J, Ye J, Zhu C, Zheng B.   +5 more
europepmc   +1 more source