Results 151 to 158 of about 2,562 (158)

Optimization of an Automated Phage Display Workflow and Isolation of Fc Knob-into-Hole specific binders

Antibodies are one of the most important entities on the therapeutics market, where modified formats such as Fabs (fragment antigen binding), the bispecifics (bsAb), or VHHs (Nanobodies) gain more and more relevance in comparison to their parental IgG formats. This is due to their various advantageous traits. In particular, bsAbs provide an opportunity
openaire   +1 more source

HOLES, KNOBS, AND WIRES

Lancet, The, 1955
exaly   +2 more sources

Targeted Gene Disruption Shows That Knobs Enable Malaria-Infected Red Cells to Cytoadhere under Physiological Shear Stress

Cell, 1997
Brendan S Crabb, Mark E Wickham, Ross L. Coppel   +2 more
exaly  

Progress in overcoming the chain association issue in bispecific heterodimeric IgG antibodies

MAbs, 2012
Christian Klein, Ulrich Brinkmann, Hubert Kettenberger   +2 more
exaly  

Preferred side-chain constellations at antiparallel coiled-coil interfaces

Proceedings of the National Academy of Sciences of the United States of America, 2008
Derek N Woolfson, Samuel H Gellman
exaly  

Optimization of Knobs-into-holes Structure of Bispecific Antibody based on Molecular Dynamics Simulation

Journal of Social Science and Humanities
openaire   +1 more source

Which knobs fit into which holes in fibrin polymerization?

Journal of Thrombosis and Haemostasis, 2007
exaly  

3D-Extraction of molecular surface knobs and holes for the study of complex formation

1992
exaly