Results 181 to 190 of about 2,501,241 (289)

Detection of insecticide resistance and knockdown resistance (<i>kdr</i>) mutations in <i>Aedes albopictus</i> across different regions. [PDF]

Front Cell Infect Microbiol
Xu N, Pan X, Peng K, Yin H, Yang Y, Han C, Gong M, Liu H.   +7 more
europepmc   +1 more source

Insecticide susceptibility status and knockdown resistance (kdr) mutation in Aedes albopictus in China. [PDF]

Parasit Vectors, 2021
Wei Y, Zheng X, He S, Xin X, Zhang J, Hu K, Zhou G, Zhong D.   +7 more
europepmc   +1 more source

Cerium Nanoparticle‐Mediated Inhibition of the NSUN2/m5C Axis Suppresses Synovial Aggression in Rheumatoid Arthritis

Advanced Science, EarlyView.
A novel epitranscriptomic mechanism in rheumatoid arthritis is uncovered: NSUN2 promotes disease via m5C‐dependent stabilization of ICMT mRNA, fueling the migration and invasion of pathogenic RA FLS. Targeting this axis with engineered nanoparticles (Ce/SAA NPs) effectively inhibits disease progression, presenting a precise therapeutic strategy ...
Ruiru Li, Simin Chen, Huijuan Hu, Shiyao Wu, Jingnan Wang, Kai Sun, Chenxi Peng, Suling Liu, Shuoyang Zhang, Yu Kuang, Wei Chen, Qian Qiu, Liuqin Liang, Yu Wen, Hanshi Xu, Youjun Xiao   +15 more
wiley   +1 more source

Knockdown resistance (kdr) mutations in the Japanese encephalitis virus vector Culex tritaeniorhynchus from the Republic of Korea. [PDF]

Trop Med Health
Jeon J, Hwang S, Choi KS.
europepmc   +1 more source

Knockdown resistance mutations distribution and characteristics of Aedes albopictus field populations within eleven dengue local epidemic provinces in China. [PDF]

Front Cell Infect Microbiol, 2022
Zhao C, Zhou X, Xue C, Lun X, Li W, Liu X, Wu H, Song X, Wang J, Liu Q, Meng F.   +10 more
europepmc   +1 more source

ANXA2+ Small Extracellular Vesicles Drive Chemoresistance in Anaplastic Thyroid Cancer by Promoting XRCC5 Lactylation and Enhancing Non‐Homologous End‐Joining Repair

Advanced Science, EarlyView.
ANXA2+ sEVs promote cisplatin resistance in ATC by stabilizing the SRC/LDHA interaction, increasing LDHA phosphorylation and activity, and lactate production. Elevated lactate levels promote KAT5‐mediated lactylation of XRCC5 at lysine 265, enhancing its binding to XRCC6.
Shanshan Su, YiShan Xiong, Yuxuan Liang, Xiang Min, Daofeng Dai   +4 more
wiley   +1 more source

Insecticidal and knockdown resistance status of Anopheles gambiae s.l (Diptera: Culicidae) to pyrethroid and organophosphate insecticides in Osun State, Nigeria. [PDF]

PLoS One
Busari LO, Iwalewa ZO, Surakat OA, Adeogun AO, Rufai AM, Fasasi KA, Adeleke MA.   +6 more
europepmc   +1 more source

Penfluridol Triggers GSDME‐Mediated Immunogenic Pyroptosis to Potentiate Antitumor Immunotherapy

Advanced Science, EarlyView.
A high‐throughput screen of FDA‐approved antipsychotics identifies penfluridol as a potent pyroptosis inducer acting via direct TTI1 inhibition. This triggers TNFA‐NFKB signaling and caspase‐8/‐3‐dependent GSDME cleavage. The compound stimulates antitumor immunity alone and synergizes with anti‐PD‐1 therapy, while low TTI1 expression emerges as a ...
Linfeng Li, Daishi Li, Danyao Chen, Yating Dian, Lei Yao, Hui Su, Ziyu Guo, Deze Zhao, Zihua Wu, Furong Zeng, Chunfang Zhang, Guangtong Deng   +11 more
wiley   +1 more source

Liver Endothelia Orchestrate MASH‐Associated Macrophage Zonation Through FSTL1‐ITGA4 Axis

Advanced Science, EarlyView.
Liver inflammation in MASH fundamentally hinges on the newly defined Kit/STAT2/FSTL1/ITGA4 axis. Declining endothelial Kit collapses normal hepatic zonation, driving an aberrant FSTL1 gradient that recruits pathogenic macrophages. Strikingly, targeting FSTL1‐ITGA4 with anti‐VLA4 restores spatial immune homeostasis and halts disease progression ...
Lin Sun, Zhensheng Yue, Zhiqiang Fang, Hao Xu, Wei Du, Yuwei Ling, Jingjing Liu, Ping Song, Fei He, Juanli Duan, Lin Wang   +10 more
wiley   +1 more source

Mutation in the knockdown resistance gene and population genetic structure in Culex tritaeniorhynchus from Guizhou Province. [PDF]

Parasit Vectors
Li W, Liu Z, Tang X, Liu C, Wang L, Deng K, Liu L, Wu J.   +7 more
europepmc   +1 more source