Results 11 to 20 of about 3,954 (184)

Three-Component Condensation of β-Ketonitriles, 4-Fluorobenzaldehyde, and Secondary Cyclic Amines

Reactions, 2022
A new three-component condensation of β-ketonitriles, 4-fluorobenzaldehyde, and secondary cyclic amines was developed. A possible reaction mechanism has been proposed including Knoevenagel condensation followed by aromatic nucleophilic substitution.
Dmitry V. Osipov, Kirill S. Korzhenko, Vitaly A. Osyanin   +2 more
doaj   +1 more source

Sulfated polyborate as Bronsted acid catalyst for Knoevenagel condensation

Results in Chemistry, 2022
We have developed the use of Bronsted acid for Knoevenagel condensation. Sulfated polyborate has been used for efficient Knoevenagel condensation of aromatic, heterocyclic, α,β-unsaturated, and aliphatic aldehydes in the ecologically friendly ethanol ...
Prerna Ganwir, Priyanka Bandivadekar, Ganesh Chaturbhuj   +2 more
doaj   +1 more source

Base and metal free true recyclable medium for Knoevenagel condensation reaction in SDS-ionic liquid-aqueous miceller composite system

Results in Chemistry, 2022
This paper presents for the first time a base and metal free procedure for Knoevenagel condensation reaction in a neutral medium comprises water-SDS-imidazolium ionic liquid composite system.
Sourav Chakraborty, Abhijit Rudra Paul, Swapan Majumdar   +2 more
doaj   +1 more source

Alternatives to piperidine in Knoevenagel condensation of 2-cyanoacetamide with benzaldehydes

Results in Chemistry, 2023
The Knoevenagel condensation (KC) is an important reaction known in organic chemistry for over a century. The catalytic version of this transformation, often with the use of piperidine as the catalyst, gained more attention in recent decades.
Jozef Stec, William H. Witola
doaj   +1 more source

Multifunctional periodic mesoporous organosilica supported dual imidazolium ionic liquids as novel and efficient catalysts for heterogeneous Knoevenagel condensation

Journal of Saudi Chemical Society, 2019
A type of multifunctional periodic mesoporous organosilica supported dual imidazolium ionic liquids PMO-IL-anion have been designed and prepared, characterized and evaluated as heterogeneous catalysts for the Knoevenagel condensation.
Nan Yao, Jin Tan, Xiang Liu, Yang Liu, Yu Lin Hu   +4 more
doaj   +1 more source

Microwave Assisted Synthesis of Indole Substituted Alkenes Using Knoevenagel Condensation Reaction and their Antibacterial Activity Study

E-Journal of Chemistry, 2010
The reaction rate of Knoevenagel condensation can be dramatically enhanced by irradiating the reaction mixture containing an aldehyde, active methylene compound, L-proline and chlorobenzene with a commercial microwave oven.
Shubha Jain, B. Nagi Reddy, K. Sambasiva Rao, G. Neeliah   +3 more
doaj   +1 more source

Nitrogen-Doped Activated Carbon as Metal-Free Catalysts Having Various Functions

C, 2017
Nitrogen-doped carbon materials have been gaining increasing interest as metal-free catalysts. In this article, the authors have briefly introduced their recent studies on the utilization of nitrogen-doped activated carbon (N-AC) for several organic ...
Shin-Ichiro Fujita, Hiroshi Yoshida, Masahiko Arai   +2 more
doaj   +1 more source

Novel DBU-based hydroxyl ionic liquid for efficient Knoevenagel reaction in water

Green Chemistry Letters and Reviews, 2019
Novel ionic liquid N-(2-hydroxy-ethyl)-DBU bromide ([HyEtDBU]Br), based on 1,8-diazabicyclo(5.4.0)undec-7-ene (DBU) and 2-bromoethanol, was introduced as catalyst for Knoevenagel condensation.
Sanhu Zhao, Dan Meng, Lingling Wei, Yongsheng Qiao, Fugui Xi   +4 more
doaj   +1 more source

Synthesis of 1,2,6-Thiadiazin 1,1-Dioxide Derivatives as Trypanocidal Agents

Molecules, 2000
It describes the synthesis of new 1,2,6-Thiadiazin 1,1-dioxide derivatives using condensation of the Knoevenagel type. The products are evaluated in vitro as trypanocidal agents.
H. Cerecetto, R. Di Maio, G. Seoane, C. Ochoa, S. Muelas, A. Gómez-Barrio   +5 more
doaj   +1 more source

Primary amine-functionalized mesoporous phenolic resin as an effective and stable solid base catalyst for Knoevenagel reactions in water

Green Synthesis and Catalysis, 2020
A primary amine functionalized ordered mesoporous phenolic resin (NH2-MPR) was obtained by an evaporation-induced self-assembly method. The as-prepared NH2-MPR material possessed large surface area and ordered two-dimensional hexagonal mesoporous ...
Kaixuan Wang, Huating Jiang, Min Tong, Yao Xiao, Hexing Li, Fang Zhang   +5 more
doaj   +1 more source