Results 141 to 150 of about 556,186 (309)

Transgressive Knowing

open access: yesJournal of Awareness-Based Systems Change
This issue's In-Dialogue represents the intentional epitomization of many conversations the Editorial Team has been having since JASC’s inception around what we mean by 'transformative'.
Oliver Koenig   +7 more
doaj   +1 more source

First Smoke

open access: yes, 2018
Trial one. Gauging the temperature of metal for varnishing. This trial showed that the varnish first began to smoke when the metal started to turn blue. Celine Camps, 2018. © Making and Knowing Project (CC BY-NC-SA)
The Making and Knowing Project
core   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Sosyal Bilimler Felsefesi Açısından Bil(in)mek ve Kur’an

open access: yesEskiyeni, 2013
İnsanoğlu çevresiyle farklı şekil ve düzeylerde ilişkiler kurar. Bu yazıda bu ilişkilerden “tanıma ve bilme” adı verilen ilişki sosyal bilimler felsefesi açısından ele alınacaktır.
Murat Kayacan
doaj  

Painting in Oil on Taffeta

open access: yes, 2017
This video shows the reconstruction process and results for the two entries about painting in oil on taffeta in Ms. Fr. 640. Sumeyye Yar, 2017. © Making and Knowing Project (CC BY-NC-SA)
The Making and Knowing Project
core   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Brazilwood Color Change

open access: yes, 2015
Video showing change of color from red to white “wine” upon addition of lemon juice to beaker containing 40 ml of red brazilwood water. Sayantani Mukherjee and Danielle Carr, 2015. © Making and Knowing Project (CC BY-NC-SA)
The Making and Knowing Project
core   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

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