Results 131 to 140 of about 556,186 (309)
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Knowing sounds: podcasting as disruptive academic practice
, 2016 Knowing Sounds is an experimental podcast exploring the possibilities and outcomes of using the podcast medium as a creative practice underpinned by conceptual thought to produce and disseminate academic research. The podcast, which more specifically can
Llinares, Dario +2 more
core
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
, 2015 Failure to secure the bundled fur in the quill ferrule. Danielle Carr, 2015. © Making and Knowing Project (CC BY-NC-SA)
The Making and Knowing Project
core +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Writers' journeys: ways of being, knowing and doing
, 2014 Traditionally, reading and writing have been recognised as characteristics of a literate person. However, literacy educators generally acknowledge that becoming literate is a complex and dynamic process that incorporates much more than learning basic ...
Henderson, Robyn
core
, 2018 A modern technique of blackening metal. Celine Camps, Jeff Wasson’s Workshop, Queens, 2019. © Making and Knowing Project (CC BY-NC-SA)
The Making and Knowing Project
core +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Dini Araştırmalar, 2015 The purpose of this study is to determine how individuals define the concepts of knowing/ knowledge and believing/belief. Another purpose was to explore the subjects understanding of presented knowledge or belief self discovered knowledge or belief For ...
Öznur Özdoğan +1 more
doaj