Results 81 to 90 of about 1,037,693 (300)
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Knowledge sharing in organizations: Roles of beliefs, training, and perceived organizational support
Knowledge Management & E-Learning: An International Journal, 2018 The main objective of this study was to test the effects of two types of beliefs about knowledge sharing, i.e., individual and collective, on the intention and behavior of knowledge sharing.
Delio Ignacio Castaneda +1 more
doaj
Molecular Oncology, EarlyView.BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
Indian Journal of Science and Technology, 2016 Objectives: This study aims to shed light on the factors that influence mobile social networking applications (Wechat) users' intention and behaviors to share knowledge from the perspective of both media and psychological features. Methods/Statistical analysis: This research conducted questionnaire survey via online survey company (Wenjuanxing) and 197
Guozhong Li, Hong Jin, Seong-Taek Park
openaire +3 more sources
Kepemimpinan Transformasional, Kepercayaan dan Berbagi Pengetahuan dalam Organisasi
Jurnal Psikologi, 2015 Many research in knowledge sharing has focused their attention on the roles of information and technology factor. Recently, there is a consideration that human factors such as social interaction, trust and leadership play keyrole in knowledge sharing ...
Avin Fadilla Helmi, Iman Arisudana
doaj +1 more source
Jurnal Manajemen Universitas Bung Hatta, 2020 Organizational citizenship behavior has been recognized as an important variable for every organization both in academicians and practitioners. The purpose of this study is to investigate the role of organizatinal citizenship behavior as mediator on the ...
Tri Sukma +2 more
doaj +1 more source
Translating whole‐genome doubling into precision medicine in cancer
Molecular Oncology, EarlyView.Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley +1 more source
Evolutionary Game Analysis on Knowledge-Sharing Behavior in the Construction Supply Chain
Sustainability, 2019 With the increasingly fierce global competition, supply chain members have to collaborate to respond to constant changes. Efficient knowledge sharing is the basis for the collaborative operation of the supply chain. Combined with evolutionary game theory,
Chanchan Hao +4 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant +7 more
wiley +1 more source
Molecular Oncology, EarlyView.Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source