Results 81 to 90 of about 1,325,679 (296)

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

Investigating the Status of Knowledge Sharing and Its Relationship with Innovative Work Behavior of Employees (Case Study: Manufacturing Company) [PDF]

مدیریت راهبردی دانش سازمانی, 2022
The innovative behavior of employees in the role of the main students of the organization, especially in manufacturing companies, is essentially subject to the behavior of their knowledge in the workplace. This is at the individual level depending on the
Farzaneh Reyhani Shukkat Abad, Rezvan Hosseingholizadeh, Alireza Khorakiyan   +2 more
doaj  

Initiating private-collective innovation: The fragility of knowledge sharing [PDF]

, 2010
Incentives to innovate are a central element of innovation theory. In the private-investment model, innovators privately fund innovation and then use intellectual property protection mechanisms to appropriate returns from these investments.
Arrow, Baldwin, Bellemare, Bergquist, Bessen, Boldrin, Brandts, Brandts, Broothaerts, Cabrera, Camerer, Casadesus-Masanell, Charness, Dasgupta, de Vries, Demsetz, di Norcia, Dufwenberg, Elster, Engelmann, Falk, Faraj, Fehr, Fehr, Feldman, Fischbacher, Foss, Foss, Franke, Garud, Georg von Krogh, Grant, Hargrave, Harhoff, Henkel, Hertel, Holmstrom, Hope, Huber, Jefferson, Jeppesen, Kim, Kogut, Kogut, Kogut, Kuk, Lakhani, Lakhani, Leonard-Barton, Lerner, Lerner, Meloso, Michailova, Montmarquette, Moody, Moon, Nonaka, Nonnecke, Olson, Osterloh, Osterloh, O’Mahony, Rabin, Raymond, Roberts, Ryan, Selten, Shah, Simon Gächter, Smith, Stefan Haefliger, Stephan, Stuermer, Szulanski, Takeishi, Teece, Teece, Useem, von Hippel, von Hippel, von Hippel, von Krogh, Wasko, Weber, Weber, Weber, Zwick   +86 more
core   +1 more source

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

FEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi, Zainab Quraishi, Shima Khezri Azizi Far, Madaleine Ward, Aidan Conway, Reem Abdulredha, Eman Mshari, Yousif A. Shamsaldeen   +7 more
wiley   +1 more source

Adoption of Web based Knowledge Sharing system amongst Academic Staff

, 2017
Knowledge sharing has been considered a significant component of success in Knowledge Management (KM). In most organizations KM is often inadequate when it comes to knowledge sharing.
Alotaibi, Hanan, Crowder, Richard, Wills, Gary   +2 more
core   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Relational Model Conflicts in Knowledge Sharing Behavior [PDF]

, 2013
The distributed nature of organizational knowledge makes that knowledge sharing an important factor for unlocking its potential value. In practice, however, people may have different motivations for not sharing knowledge with colleagues, which in part ...
Baalen, P.J. (Peter) van, Dalen, J. (Jan) van, Malsen, J. (Jorina) van   +2 more
core  

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

Assessing the relationship between supervisor knowledge sharing and innovative behaviors among clinical nurses: the mediating role of organizational learning

BMC Nursing
Background In today’s rapidly evolving healthcare environment, nurses’ innovative behaviors are crucial for improving patient care quality and organizational effectiveness.
Nima Gharajeh-Alamdari, Alireza Mirzaei, Saeid Mehri, Aghil Habibi Soola   +3 more
doaj   +1 more source

An Agent-Based System with Personalization and Intelligent Assistance Services for Facilitating Knowledge Sharing [PDF]

, 2006
The scenario of distributed knowledge in organization, lack of understanding of knowledge sharing benefits and technology inadequacies are the main barriers to knowledge sharing facilitation.
Mohd Sharef, Nurfadhlina
core