Results 121 to 130 of about 22,283,149 (341)
Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA
Molecular Oncology, EarlyView.Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson +2 more
wiley +1 more source
, 2004 [From Introduction] The country study for Kenya is part of the ILO project \u27Employment of People with Disabilities – the Impact of Legislation\u27, funded by the Government of Ireland, which aims to enhance the capacity of national governments in ...
InFocus Programme on Skills, Knowledge and Employability +1 more
core +1 more source
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
, 2003 [From Introduction] This country study for Fiji is part of the ILO project \u27Employment of People with Disabilities – the Impact of Legislation\u27 which aims to enhance the capacity of national governments in selected countries of Asia and East Africa
ILO InFocus Programme on Skills, Knowledge and Employability +1 more
core +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
, 2003 [From Introduction] This country study for Japan is part of the ILO project \u27Employment of People with Disabilities – the Impact of Legislation\u27 which aims to enhance the capacity of national governments in selected countries of Asia and East ...
InFocus Programme on Skills, Knowledge and Employability +1 more
core +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Chiropractic & Manual TherapiesBackground The evidence on age-related differences in outcomes in patients seeking chiropractic care for low back pain is limited. The aims of this study were to (i) to explore differences in patient characteristics and symptoms between older, middle ...
L. A. Hansen +2 more
doaj +1 more source
Knowledge, Attitude and Practice of Cervical Cancer Screening Through Visual Inspection with Acetic Acid [PDF]
, 2017 Detection of the cervical cancer requires practice of screening that will increase survival rates from the disease. Visual Inspection with Acetic Acid (VIA) is an alternative to screening for cervical cancer.This study aims to assess the knowledge ...
Ahmed, M. K. (Md), Kar, S. (Susmita)
core