Results 121 to 130 of about 21,646,956 (389)

Data‐driven discovery of gene expression markers distinguishing pediatric acute lymphoblastic leukemia subtypes

open access: yesMolecular Oncology, EarlyView.
This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh   +8 more
wiley   +1 more source

Sudan Country Profile [PDF]

open access: yes, 2004
[From Introduction] The country study for Sudan is part of the ILO project \u27Employment of People with Disabilities – the Impact of Legislation\u27, funded by the Government of Ireland, which aims to enhance the capacity of national governments in ...
ILO InFocus Programme on Skills, Knowledge and Employability   +1 more
core   +1 more source

TRPM8 levels determine tumor vulnerability to channel agonists

open access: yesMolecular Oncology, EarlyView.
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo   +18 more
wiley   +1 more source

Mongolia Country Profile [PDF]

open access: yes, 2003
[From Introduction] This country study for Mongolia is part of the ILO project \u27Employment of People with Disabilities – the Impact of Legislation\u27 which aims to enhance the capacity of national governments in selected countries of Asia and East ...
Infocus Programme on Skills, Knowledge and Employability/Disability Programme   +1 more
core   +1 more source

The anticancer effect of the HDAC inhibitor belinostat is enhanced by inhibitors of Bcl‐xL or Mcl‐1 in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine   +10 more
wiley   +1 more source

Dimensions of the Smart Home Ontology for Elderly People [PDF]

open access: yesIranian Journal of Information Processing & Management
According to the official statistics of the country's population, it is predicted that in the next twenty years, more than a quarter of the population will be elderly.
Najme Nazeri   +2 more
doaj   +1 more source

Policies for capacity development [PDF]

open access: yes, 2012
No description ...
Abdel Gelil, Ibrahim   +10 more
core   +1 more source

Dose‐dependent induction of epithelial‐mesenchymal transition in 3D melanoma models by non‐thermal plasma treatment

open access: yesMolecular Oncology, EarlyView.
Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop   +10 more
wiley   +1 more source

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