Results 71 to 80 of about 17,170,100 (315)

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

Use of implementation science methods to design Wellness Hub, a responsive program to address long-term care and retirement homes’ challenges during the COVID-19 pandemic

BMC Health Services Research
Background Long-term care and retirement homes (LTCH/RH) faced systemic challenges that were exacerbated by the COVID-19 pandemic. Homes faced three major challenges over the course of the pandemic: implementing infection prevention and control (IPAC ...
Christine Fahim, Keelia Quinn de Launay, Vanessa Bach, Jessica Firman, Claire R. Gapare, Vincenza Gruppuso, Ayaat T. Hassan, Ana Mrazovac, Temi Odunuga, Nimitha Paul, Lisa Strifler, Alyson Takaoka, Elikem Togo, Hui Juan Chelsea Gao, Jamie M. Boyd, Sharon E. Straus   +15 more
doaj   +1 more source

Decoding the future of agricultural participation: machine learning insights to unravel the plausible triggers

Frontiers in Applied Mathematics and Statistics
IntroductionAs agricultural participation continues to shift under the pressures of urbanization, climate change, and evolving socioeconomic conditions, understanding the drivers behind household engagement becomes increasingly vital.MethodsThis study ...
Katiso Ramalebo, Retius Chifurira, Temesgen Zewotir, Knowledge Chinhamu   +3 more
doaj   +1 more source

Open Knowledge Maps: Visuelle Literatursuche basierend auf den Prinzipien von Open Science

Mitteilungen der Vereinigung Österreichischer Bibliothekarinnen und Bibliothekare, 2019
Die Wissenschaft befindet sich in einer Auffindbarkeitskrise. Obwohl durch die Open Access-Bewegung Forschungsergebnisse besser zugänglich geworden sind, wird ein signifikanter Teil der Outputs nicht nachgenutzt.
Peter Kraker, Maxi Schramm, Christopher Kittel   +2 more
doaj   +1 more source

Discussion paper: Disability and poverty reduction strategies: How to ensure that access of persons with disabilities to decent and productive work is part of the PRSP process [PDF]

, 2002
[Excerpt] In 1999, the IMF and the World Bank launched the Poverty Reduction Strategy Paper (PRSP) approach to poverty reduction in low-income countries in order to ensure that concessional funding through the IMF’s Poverty Reduction and Growth ...
InFocus Programme on Skills, Knowledge and Employability, Roeske, Hans   +1 more
core   +1 more source

Knowledge and Sensory Knowledge in Hume's _Treatise_ [PDF]

, 2021
I argue that the Hume of the Treatise maintains an account of knowledge according to which (i) every instance of knowledge must be an immediately present perception (i.e., an impression or an idea); (ii) an object of this perception must be a token of a ...
Clay, Graham
core  

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Ethiopia Country Profile [PDF]

, 2003
[From Introduction] The country study for Ethiopia is part of the ILO project \u27Employment of People with Disabilities – the Impact of Legislation\u27, funded by the Government of Ireland, which aims to enhance the capacity of national governments in ...
InFocus Programme on Skills, Knowledge and Employability, International Labour Office   +1 more
core   +2 more sources

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

The effects of home and school on children’s happiness: a structural equation model

International Journal of Child Care and Education Policy, 2018
This study analyzed the structural relationships between the important constructs of school, home and family, and the happiness of Abu Dhabi school children. Survey data were collected from students in schools in the three regions of Abu Dhabi. The final
Masood Badri, Ali Al Nuaimi, Yang Guang, Yousef Al Sheryani, Asma Al Rashedi   +4 more
doaj   +1 more source