Results 81 to 90 of about 11,762,702 (302)
Accessible Knowledge—Knowledge on Accessibility [PDF]
Journal of Civil Engineering and Architecture, 2015 Although serious efforts are made internationally and nationally, it is a slow process to make our physical environment accessible. In the actual design process, architects play a major role. But what kinds of knowledge– including research-based knowledge – do practicing architects make use of when designing accessible environments?
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FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
BMC Health Services ResearchBackground Long-term care and retirement homes (LTCH/RH) faced systemic challenges that were exacerbated by the COVID-19 pandemic. Homes faced three major challenges over the course of the pandemic: implementing infection prevention and control (IPAC ...
Christine Fahim +15 more
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The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
PHILOSOPHICAL KNOWLEDGE AND KNOWLEDGE OF COUNTERFACTUALS
Grazer Philosophische Studien, 2007 Metaphysical modalities are definable from counterfactual conditionals, and the epistemology of the former is a special case of the epistemology of the latter. In particular, the role of conceivability and inconceivability in assessing claims of possibility and impossibility can be explained as a special case of the pervasive role of the imagination in
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Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers
FEBS Letters, EarlyView.Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui +4 more
wiley +1 more source
FEBS Letters, EarlyView.Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil +3 more
wiley +1 more source
FEBS Letters, EarlyView.Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise +5 more
wiley +1 more source
Open Knowledge Maps: Visuelle Literatursuche basierend auf den Prinzipien von Open Science
Mitteilungen der Vereinigung Österreichischer Bibliothekarinnen und Bibliothekare, 2019 Die Wissenschaft befindet sich in einer Auffindbarkeitskrise. Obwohl durch die Open Access-Bewegung Forschungsergebnisse besser zugänglich geworden sind, wird ein signifikanter Teil der Outputs nicht nachgenutzt.
Peter Kraker +2 more
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