Results 61 to 70 of about 1,066,315 (259)

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Knowledge Management Factors as Building Blocks of Quality of Care in Healthcare Systems

Organizacija
The aim of the study was to review national and international professional literature on the impact of knowledge management factors on the quality of care in healthcare systems.
Krišelj Tadeja, Markič Mirko, Zoran Annmarie Gorenc, Kolnik Tamara Štemberger   +3 more
doaj   +1 more source

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

Molecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen, Zhi Zhao, Henrik Horndalsveen, Maria Moksnes Bjaanæs, Bjørn Henning Grønberg, Tarje Halvorsen, Tesfaye Madebo, Marianne Aanerud, Jussi Koivunen, Kersti Oselin, Saulius Cicenas, Nina Helbekkmo, Jarkko Ahvonen, Maria Silvoniemi, Tine Norman Alver, Tonje Dalen, Åsa Kristina Öjlert, Saima Jamil Farooqi, Åslaug Helland, Vilde Drageset Haakensen   +19 more
wiley   +1 more source

Explicit and implicit knowledge with regard to the age of learners

ExELL (Explorations in English Language and Linguistics), 2013
The present study set out to examine learners’ explicit and implicit foreign language knowledge with regard to their age. Therefore, two groups of learners from Zenica and Zavidovići (Bosnia and Herze-govina) presented the pool of informants in this ...
Vildana Dubravac
doaj  

Comparison of teleportation and walking in virtual reality in a declarative learning task

Frontiers in Virtual Reality
IntroductionVirtual reality (VR) offers new possibilities for learning in educational settings by navigating through large 3D virtual environments. When designing VR-based learning applications, developers have to decide between different locomotion ...
Michael Rihs, Michael Rihs, Rahel A. Steuri, Sarah A. Aeschlimann, Fred W. Mast, Martin Dobricki   +5 more
doaj   +1 more source

NAPRT loss promotes lung tumor initiation and growth through AKT signaling independently of NAD+ biosynthesis

Molecular Oncology, EarlyView.
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh, Ji Yun Jang, Yoon Jeon, Gi‐Cheon Kim, Hwanho Lee, Jooyoung Lee, Ju‐Hwa Kim, Hakhyun Kim, Minjee Kim, Ho‐Keun Kwon, Ho Lee, Hyun Seok Kim   +11 more
wiley   +1 more source

Toward Sustainable Digital Literacy: A Comparative Study of Gamified and Non-Gamified Digital Board Games in Higher Education

Education Sciences
This study examines the effects of gamified and non-gamified digital board games on students’ digital literacy and engagement. A total of 98 undergraduate students (n = 98) were randomly assigned to one of two conditions: gamified or non-gamified.
Songpon Khanchai, Perasuk Worragin, Pakinee Ariya, Kannikar Intawong, Kitti Puritat   +4 more
doaj   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

Knowledge Acquisition for Diagnosis of Skin Diseases as an Initial Platform for an Expert System

Journal of Health Management & Informatics, 2018
Background: The diagnosis of skin diseases, especially in patients suffering from more than one disease or having similar symptoms, is very complex and access to the knowledge of skin diseases makes the design of an expert system easier.
Fatemeh Rangraz Jeddi, Masoud Arabfard, Zahra Arab Kermani   +2 more
doaj  

Knowledge Acquisition Approach Based On Svm In An Online Aided Decision System For Food Processing Quality And Safety

Cybernetics and Information Technologies, 2014
In connection with the problem that the food processing information system is poor due to the absence of knowledge acquisition and a knowledge selfupdating function, a knowledge acquisition approach, based on a Support Vector Machine (SVM) is proposed ...
Peng Liu, Wen Liu, Li Yang, Qiang Li, Min Duan, Yue Dai   +5 more
doaj   +1 more source