Results 101 to 110 of about 4,480,263 (341)

Building Knowledge Bases for the Generation of Software Documentation

open access: yes, 1996
Automated text generation requires a underlying knowledge base from which to generate, which is often difficult to produce. Software documentation is one domain in which parts of this knowledge base may be derived automatically.
Linden, Keith Vander, Paris, Cecile
core   +3 more sources

The anticancer effect of the HDAC inhibitor belinostat is enhanced by inhibitors of Bcl‐xL or Mcl‐1 in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine   +10 more
wiley   +1 more source

Dose‐dependent induction of epithelial‐mesenchymal transition in 3D melanoma models by non‐thermal plasma treatment

open access: yesMolecular Oncology, EarlyView.
Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop   +10 more
wiley   +1 more source

Research on ontology-based construction risk knowledge base development in deep foundation pit excavation

open access: yesJournal of Asian Architecture and Building Engineering
Facing the massive amount of risk management data for deep foundation pit excavation (DFPE) construction, how to store and utilize these data to prevent the occurrence of risk events is an urgent problem that needs to be solved. The goal of this research
Yuan Chen, Bingge Liang, Hang Hu
doaj   +1 more source

Molecular imaging predicts trastuzumab‐deruxtecan (T‐DXd) response in head and neck cancer xenograft models

open access: yesMolecular Oncology, EarlyView.
Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed   +8 more
wiley   +1 more source

Flabase: towards the creation of a flamenco music knowledge base [PDF]

open access: yes, 2015
Online information about flamenco music is scattered overdifferent sites and knowledge bases. Unfortunately, thereis no common repository that indexes all these data. Inthis work, information related to flamenco music is gath-ered from general
Gómez Gómez, Francisco   +5 more
core  

Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma

open access: yesMolecular Oncology, EarlyView.
GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski   +19 more
wiley   +1 more source

Home - About - Disclaimer - Privacy