Results 151 to 160 of about 1,501,913 (314)

MCF2Chem: A manually curated knowledge base of biosynthetic compound production. [PDF]

open access: yesBiotechnol Biofuels Bioprod, 2023
Cai P, Liu S, Zhang D, Hu QN.
europepmc   +1 more source

Common Sense Enhanced Knowledge-based Recommendation with Large Language Model [PDF]

open access: yesarXiv
Knowledge-based recommendation models effectively alleviate the data sparsity issue leveraging the side information in the knowledge graph, and have achieved considerable performance. Nevertheless, the knowledge graphs used in previous work, namely metadata-based knowledge graphs, are usually constructed based on the attributes of items and co ...
arxiv  

Highly multiplexed digital PCR assay for simultaneous quantification of variant allele frequencies and copy number alterations of KRAS and GNAS in pancreatic cancer precursors

open access: yesMolecular Oncology, EarlyView.
Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka   +10 more
wiley   +1 more source

Technological Process Modeling For Castings According To Specified Parameters Of Output Production Quality Based On Production-Frame Model Of Knowledge Representation

open access: yesAstra Salvensis, 2017
The article considers the modeling technique of casting technological process according to the required quality indicators of output products. They proposed the structure of an intellectual information system based on the presentation of knowledge using
Linar R. YUSUPOV, Dmitry N. DEMYANOV
doaj  

Biomedical relation extraction with knowledge base-refined weak supervision. [PDF]

open access: yesDatabase (Oxford), 2023
Yoon W   +5 more
europepmc   +1 more source

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

open access: yesMolecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes   +20 more
wiley   +1 more source

A multi-scale expression and regulation knowledge base for Escherichia coli. [PDF]

open access: yesNucleic Acids Res, 2023
Lamoureux CR   +7 more
europepmc   +1 more source

Germline variants in CDKN2A wild‐type melanoma prone families

open access: yesMolecular Oncology, EarlyView.
Among melanoma‐prone families, wild‐type for CDKN2A and CDK4, some have pathogenic variants in genes not usually linked to melanoma. Furthermore, rare XP‐related variants and variants in MC1R are enriched in such families. Germline pathogenic variants in CDKN2A are well established as an underlying cause of familial malignant melanoma. While pathogenic
Gjertrud T. Iversen   +5 more
wiley   +1 more source

КОНЦЕПЦІЯ ВИКОРИСТАННЯ ГЕОІНФОРМАТИКИ В ПОБУДОВІ ІНФОРМАЦІЙНО-КЕРУЮЧОЇ СИСТЕМИ «ВИЩА ШКОЛА УКРАЇНИ»

open access: yesІнформаційні технології і засоби навчання, 2010
У статті викладені основні концептуальні положення використання методів геоінформатики для побудови інформаційно-керуючої системи «вища школа України».
Kostiantyn O. Meteshkin   +2 more
doaj  

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