Results 151 to 160 of about 35,424,542 (378)
Molecular Oncology, EarlyView.Small extracellular vesicles are a promising source of diagnostic molecules. We conducted a comprehensive study, including transcriptome profiling and RT‐qPCR validation on large cohorts of samples. Diagnostic panels enabling sensitive detection of colorectal cancer and precancerous lesions were established. Some molecules were differentially expressed
Petra Vychytilova‐Faltejskova +26 more
wiley +1 more source
A knowledge-based code generator generator [PDF]
, 1977 Christopher W. Fraser
openalex +1 more source
Molecular Oncology, EarlyView.Proteomic and phosphoproteomic analyses were performed on lung adenocarcinoma (LUAD) tumors with EGFR, KRAS, or EML4–ALK alterations and wild‐type cases. Distinct protein expression and phosphorylation patterns were identified, especially in EGFR‐mutated tumors. Key altered pathways included vesicle transport and RNA splicing.
Fanni Bugyi +12 more
wiley +1 more source
Cybernetics and Information Technologies, 2015 With regard to the inefficient application of a food processing information system due to shortage of the knowledge acquisition measure and self-updating function of knowledge, a method of constructing an online aided decision making knowledge base for ...
Wen Liu +5 more
doaj +1 more source
Molecular Oncology, EarlyView.RKIP, a metastasis suppressor protein, modulates key oncogenic pathways in lung adenocarcinoma. In silico analyses linked low RKIP expression to poor survival. Functional studies revealed RKIP overexpression reduces tumor aggressiveness and enhances sensitivity to EGFR‐targeted therapies, while its loss promotes resistance.
Ana Raquel‐Cunha +10 more
wiley +1 more source
Learning translation skills with a knowledge-based tutor [PDF]
, 1983 Stefano A. Cerri, Marie-France Merger
openalex +1 more source
Decrypting cancer's spatial code: from single cells to tissue niches
Molecular Oncology, EarlyView.Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik +4 more
wiley +1 more source
INTELLECTUAL ELECTRONIC DOCUMENTATION OF TECHNOLOGICAL OBJECTS IN PLM SYSTEM
Advanced Engineering Research, 2011 An innovative approach to the documentation of technological objects is presented. Recommendations and methods for the development of the intellectual passport for technological objects in PLM system, its knowledge bases, organizations, data and ...
Andrey K. Tugengold +3 more
doaj
DECISION MAKING PROCESS IN CARDIAC SURGERY – CONCEPT OF BUILDING AN EXPERT SYSTEM [PDF]
Management Systems in Production Engineering, 2013 The fundamental goal of modern information technology is to support decision making process in organizations, for both routine and highly complex problems, based on heterogeneous data sources.
Tomasz HRAPKOWICZ +4 more
doaj
Avalanche Starting-Zone Analysis by use of a Knowledge-Based System [PDF]
, 1989 Laurent Buisson, Claude Charlier
openalex +1 more source