Results 61 to 70 of about 1,501,913 (314)

Predicting Completeness in Knowledge Bases [PDF]

open access: yesProceedings of the Tenth ACM International Conference on Web Search and Data Mining, 2017
Knowledge bases such as Wikidata, DBpedia, or YAGO contain millions of entities and facts. In some knowledge bases, the correctness of these facts has been evaluated. However, much less is known about their completeness, i.e., the proportion of real facts that the knowledge bases cover.
Galárraga, Luis   +3 more
openaire   +5 more sources

Characteristics of the Kelch domain containing (KLHDC) subfamily and relationships with diseases

open access: yesFEBS Letters, EarlyView.
The Kelch protein superfamily includes 63 members, with the KLHDC subfamily having 10 proteins. While their functions are not fully understood, recent advances in KLHDC2's structure and role in protein degradation have highlighted its potential for drug development, especially in PROTAC therapies.
Courtney Pilcher   +6 more
wiley   +1 more source

The multiple roles of the NlpC_P60 peptidase family in mycobacteria – an underexplored target for antimicrobial drug discovery

open access: yesFEBS Letters, EarlyView.
The NlpC_P60 superfamily of peptidases is recognised by its key role in bacterial cell wall homeostasis. Recently, studies have also described the involvement of NlpC_P60‐like enzymes in bacterial competitive mechanisms and pathogenesis across several lineages.
Catharina dos Santos Silva   +1 more
wiley   +1 more source

DECISION MAKING PROCESS IN CARDIAC SURGERY – CONCEPT OF BUILDING AN EXPERT SYSTEM [PDF]

open access: yesManagement Systems in Production Engineering, 2013
The fundamental goal of modern information technology is to support decision making process in organizations, for both routine and highly complex problems, based on heterogeneous data sources.
Tomasz HRAPKOWICZ   +4 more
doaj  

Regular Expression Based Online Aided Decision Making Knowledge Base for Quality and Security of Food Processing

open access: yesCybernetics and Information Technologies, 2015
With regard to the inefficient application of a food processing information system due to shortage of the knowledge acquisition measure and self-updating function of knowledge, a method of constructing an online aided decision making knowledge base for ...
Wen Liu   +5 more
doaj   +1 more source

KNOWLEDGE TRANSFER IN A KNOWLEDGE-BASED ECONOMY

open access: yesE+M Ekonomie a Management, 2016
The knowledge economy currently presupposes that each organization manages its knowledge and in doing so intentionally endeavors to achieve a long-term competitive advantage. In other words the key source of success is no longer information as such, but the right knowledge which is associated with a specifi c bearer – employee who must constantly ...
Urbancová, Hana   +2 more
openaire   +3 more sources

Refining the NaV1.7 pharmacophore of a class of venom‐derived peptide inhibitors via a combination of in silico screening and rational engineering

open access: yesFEBS Letters, EarlyView.
Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma   +8 more
wiley   +1 more source

An Integrated Model for User Innovation Knowledge Based on Super-network [PDF]

open access: yesarXiv, 2019
Online user innovation communities are becoming a promising source of user innovation knowledge and creative users. With the purpose of identifying valuable innovation knowledge and users, this study constructs an integrated super-network model, i.e., User Innovation Knowledge Super-Network (UIKSN), to integrate fragmented knowledge, knowledge fields ...
arxiv  

Knowledge-graph based Proactive Dialogue Generation with Improved Meta-Learning [PDF]

open access: yesarXiv, 2020
Knowledge graph-based dialogue systems can narrow down knowledge candidates for generating informative and diverse responses with the use of prior information, e.g., triple attributes or graph paths. However, most current knowledge graph (KG) cover incomplete domain-specific knowledge.
arxiv  

The power of microRNA regulation—insights into immunity and metabolism

open access: yesFEBS Letters, EarlyView.
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto   +2 more
wiley   +1 more source

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