Results 61 to 70 of about 4,570,213 (290)
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
FEBS Letters, EarlyView.The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Big Data and Cognitive ComputingCommunications in intelligent transportation systems (ITS) face explosive data growth from applications such as autonomous driving, remote diagnostics, and real-time monitoring, imposing severe challenges on limited spectrum, bandwidth, and latency ...
Yan Xiao +3 more
doaj +1 more source
Demand-Weighted Completeness Prediction for a Knowledge Base
, 2018 In this paper we introduce the notion of Demand-Weighted Completeness, allowing estimation of the completeness of a knowledge base with respect to how it is used.
Gurdasani, Amit +3 more
core +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Открытое образование (Москва), 2016 Article represents the features of modern educational environment for training specialists in the fi eld of aerospace robotics. Training requirements of modern specialists are pointed.
Svetlana V. Zenkina, Vasilij M. Trembach
doaj +1 more source
Neural Wikipedian: Generating Textual Summaries from Knowledge Base Triples
, 2017 Most people do not interact with Semantic Web data directly. Unless they have the expertise to understand the underlying technology, they need textual or visual interfaces to help them make sense of it.
Elsahar, Hady +6 more
core +3 more sources
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Knowledge management system as a basis for smart learning
Открытое образование (Москва), 2018 The purpose of the study is to develop an approach to improve information support for the development of the contents of higher education programs and teaching methodological materials.
Natalia V. Dneprovskaya
doaj +1 more source