Results 61 to 70 of about 841,080 (310)
Knowledge and Attitude of Nurses with Computerized Based Nursing Care Documentation [PDF]
, 2022 Antonius Janggeng +2 more
openalex +1 more source
Emerging role of ARHGAP29 in melanoma cell phenotype switching
Molecular Oncology, EarlyView.This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster +3 more
wiley +1 more source
Development of science and technology in a knowledge-based organization from the intellectual capital’s perspective [PDF]
مطالعات مدیریت راهبردی, 2020 The foundation of an organization and its transformation into a knowledge organization depend deeply on its various aspects, so that if it is not provided with its basic infrastructure and infrastructure, any attempt at it will fail.
mohammad reza zahedi +2 more
doaj
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
Knowledge Acquisition for Diagnosis of Skin Diseases as an Initial Platform for an Expert System
Journal of Health Management & Informatics, 2018 Background: The diagnosis of skin diseases, especially in patients suffering from more than one disease or having similar symptoms, is very complex and access to the knowledge of skin diseases makes the design of an expert system easier.
Fatemeh Rangraz Jeddi +2 more
doaj
Molecular Oncology, EarlyView.Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser +14 more
wiley +1 more source
Molecular Oncology, EarlyView.This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker +16 more
wiley +1 more source
Crawling the Internal Knowledge-Base of Language Models [PDF]
, 2023 Roi Cohen +3 more
openalex +1 more source
Molecular Oncology, EarlyView.This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad +17 more
wiley +1 more source
Planetary Defense Mitigation Gateway: A One-Stop Gateway for Pertinent PD-Related Contents
Data, 2019 Planetary Defense (PD) has become a critical effort of protecting our home planet by discovering potentially hazardous objects (PHOs), simulating the potential impact, and mitigating the threats.
Ishan Shams +13 more
doaj +1 more source