Results 71 to 80 of about 6,326,238 (294)

Real-time application of knowledge-based systems [PDF]

The Rapid Prototyping Facility (RPF) was developed to meet a need for a facility which allows flight systems concepts to be prototyped in a manner which allows for real-time flight test experience with a prototype system. This need was focused during the
Brumbaugh, Randal W., Duke, Eugene L.
core   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

Semantically Enhanced Medical Information Retrieval System: A Tensor Factorization Based Approach

IEEE Access, 2017
Medical information retrieval plays an increasingly important role to help physicians and domain experts to better access medical-related knowledge and information, and support decision making. Integrating the medical knowledge bases has the potential to
Haolin Wang, Qingpeng Zhang, Jiahu Yuan
doaj   +1 more source

Building validation tools for knowledge-based systems [PDF]

The Expert Systems Validation Associate (EVA), a validation system under development at the Lockheed Artificial Intelligence Center for more than a year, provides a wide range of validation tools to check the correctness, consistency and completeness of ...
Chang, C. L., Combs, J. B., Stachowitz, R. A., Stock, T. S.   +3 more
core   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

The influencing mechanism of manufacturing scene change on process domain knowledge reuse [PDF]

, 2013
It is necessary for a enterprise to reuse outside process domain knowledge to develop intelligent manufacturing technology. The key factors influencing knowledge reuse in digital manufacturing scene are manufacturing activities and PPR (Products ...
Ling, Tiezhang, Liu, Chuang, Wang, Junbiao   +2 more
core  

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Modeling State Causality in Energy Centred Cyber-Physical-Human Systems With OntoUML

IEEE Access
Energy-focused Cyber-Physical-Human Systems (CPHSs) depend on understanding how events, states, and temporal transitions shape system behaviour, particularly in settings where human actors, such as building occupants, grid operators, and domain experts ...
Mohammad Bilal, Katrin Ehrenmuller, Gernot Steindl, Zhuoxun Zheng, Shqiponja Ahmetaj, Ahmet Soylu, Emanuel Sallinger, Wolfgang Kastner   +7 more
doaj   +1 more source

Rule-based classification of energy theft and anomalies in consumers load demand profile

IET Smart Grid, 2019
The invent of advanced metering infrastructure (AMI) opens the door for a comprehensive analysis of consumers consumption patterns including energy theft studies, which were not possible beforehand. This study proposes a fraud detection methodology using
Sonal Jain, Kushan A. Choksi, Naran M. Pindoriya   +2 more
doaj   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source