Results 81 to 90 of about 1,501,270 (269)
Why human connection is the true metric of research success
FEBS Open Bio, EarlyView.Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan +3 more
wiley +1 more source
Roles of design knowledge in knowledge-based systems
International Journal of Human-Computer Studies, 1996 Abstract Recent research suggests that the abilities of a knowledge-based system (KBS) depend in part on the amount of explicit knowledge it has about the way it is designed. This knowledge is often called design knowledge because it reflects design decisions that a KBS developer makes regarding what ontologies to embody in the system, what solution ...
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FEBS Open Bio, EarlyView.The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer +7 more
wiley +1 more source
FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
Review of Knowledge-Based Systems.
AI Mag., 1989 The two-volume set entitled "Knowledge-Based Systems (Volume 1, Knowledge Acquisition for Knowledge-Based Systems, 355 pp., and Volume 2, "Knowledge Acquisition Tools for Expert Systems, 343 pp., Academic Press, San Diego, California, 1988), edited by B. R. Gaines and J. H.
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Research Involvement and EngagementBackground Young women living with perinatal infections of the Human Immunodeficiency Virus (YWLPHIV) in low- and middle-income countries are more likely to be challenged by social and health inequities, which can make adherence to life-long treatment ...
Lynn Hendricks +5 more
doaj +1 more source
FEBS Open Bio, EarlyView.Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin +3 more
wiley +1 more source
Knowledge acquisition for knowledge based decision systems
Applied Artificial Intelligence, 1997 Knowledge-based decision systems support the decision analysis process with decision analytic knowledge as well as domain-specific knowledge. The knowledge in the knowledgebased decision system is usually represented by influence diagrams. In the development of knowledge-based decision systems, knowledge acquisition is one of the most difficult ...
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Scientific ReportsWater quality prediction and management are crucial for ensuring the sustainability of water supplies. Contaminated water can harm humans and aquatic life.
Hussein Karam Abd El-Sattar +3 more
doaj +1 more source