Results 101 to 110 of about 34,204,469 (282)

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Taxonomy and Survey on Cybersecurity Control Schemes for Smart Grids

IET Smart Grid
This article presents a comprehensive taxonomy and survey of Cybersecurity Control Schemes (CCS) tailored for Smart Grids (SG), with a particular focus on vulnerabilities in the IEC 61850 standard and the countermeasures provided by IEC 62351.
Aldo Insfrán, Fabio López‐Pires, Benjamín Barán   +2 more
doaj   +1 more source

OWL2 benchmarking for the evaluation of knowledge based systems. [PDF]

PLoS One, 2017
Khan SA, Qadir MA, Abbas MA, Afzal MT, Afzal MT.   +4 more
europepmc   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Toward integration of knowledge based systems and knowledge discovery systems

Journal of Computer Science and Technology, 2007
This paper presents a proposal for an architecture that integrates knowledge discovery systems (automatic acquisition) and knowledge based systems (experts systems).
Claudio Rancan, Patricia Mabel Pesado, Ramón García Martínez   +2 more
doaj  

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Knowledge representation within information systems in manufacturing environments [PDF]

, 2004
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.Representing knowledge as information content alone is insufficient in providing us with an understanding of the world around us.
Sharif, Amir M
core   +2 more sources

‘More than a pill’: a qualitative co-exploration of the things that matter in young women's stories of adherence to antiretroviral treatment in South Africa

Research Involvement and Engagement
Background Young women living with perinatal infections of the Human Immunodeficiency Virus (YWLPHIV) in low- and middle-income countries are more likely to be challenged by social and health inequities, which can make adherence to life-long treatment ...
Lynn Hendricks, Taryn Young, Robin Julies, Rizqah Dollie, Dollie Reshaan, Karin Hannes   +5 more
doaj   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

Intelligent Support for a Computer Aided Design Optimisation Cycle

Acta Polytechnica, 2006
It is becoming more and more evident that  adding intelligence  to existing computer aids, such as computer aided design systems, can lead to significant improvements in the effective and reliable performance of various engineering tasks, including ...
B. Dolšak, M. Novak, J. Kaljun
doaj