Results 81 to 90 of about 1,689,886 (311)
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Implementing sustainability co-creation between universities and society: A typology-based understanding [PDF]
, 2017 Universities are under mounting pressure to partner with societal stakeholders and organizations to collaboratively create and implement sustainability-advancing knowledge, tools, and societal transformations.
Chen, C +9 more
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Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Co-Creation: Viewing Partnerships Through A New Lens [PDF]
, 2016 Collaboration remains an on-going discourse throughout the funder community, but little has been written about explorations or innovations into different ways of working collectively, beyond what was established decades ago.The Connecticut legislation ...
Patricia Bowie
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Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Living labs in architecture : open innovation and co-creation towards a more sustainable architecture and lifestyle [PDF]
, 2014 Living Labs in Architecture can be tools towards a holistic knowledge generation and transmission, using real built environments for user-centred research and innovation as well as collaborative learning at a university campus and beyond.
Masseck, Torsten
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An overview of three decades of mergers and acquisitions research [PDF]
, 2015 Mergers and acquisitions (M&A) have long attracted managers’ attention and have been researched in different perspectives and using different theories. In this study we grasp the wealth of extant research in the field of M&As. We conducted a bibliometric
Carvalho, Fernando +2 more
core +4 more sources
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
as Methodology: Reclaiming Indonesian Practices for Knowledge Co-Creation
International Journal of Qualitative MethodsThis paper proposes Ngopi —the culturally embedded practice of informal coffee gatherings—as a decolonial methodology for qualitative research in the Indonesian context.
Af’idatul Husniyah
doaj +1 more source
Productive in disagreement: stakeholder deliberation insights on carbon dioxide removal in Germany
Frontiers in ClimateAttention to carbon dioxide removal (CDR) in climate policy is growing, and many CDR methods such as direct air carbon capture and storage (DACCS) are controversial.
Maria Apergi +6 more
doaj +1 more source