Results 171 to 180 of about 803,882 (321)

FAM136A depletion induces mitochondrial stress and reduces mitochondrial membrane potential and ATP production

FEBS Open Bio, EarlyView.
FAM136A depletion upregulated ROS production, reduced mitochondrial membrane potential (ΔΨ) and ATP production, and upregulated expression of PCK1, PCK2, HMGCS1, and HMGCS2. The expression of both TOMM22 and TOMM20 was also upregulated. FAM136A depletion reduced HCCS that produce holocytochrome c by combining heme to apocytochrome c, and reduced the ...
Yushi Otsuka, Masato Yano
wiley   +1 more source

Injecting Linguistic Knowledge Into BERT for Dialogue State Tracking

IEEE Access
Dialogue State Tracking (DST) models often employ intricate neural network architectures, necessitating substantial training data, and their inference process lacks transparency.
Xiaohan Feng, Xixin Wu, Helen Meng
doaj   +1 more source

Beyond digital twins: the role of foundation models in enhancing the interpretability of multiomics modalities in precision medicine

FEBS Open Bio, EarlyView.
This review highlights how foundation models enhance predictive healthcare by integrating advanced digital twin modeling with multiomics and biomedical data. This approach supports disease management, risk assessment, and personalized medicine, with the goal of optimizing health outcomes through adaptive, interpretable digital simulations, accessible ...
Sakhaa Alsaedi, Xin Gao, Takashi Gojobori   +2 more
wiley   +1 more source

Combining language models for knowledge extraction from Italian TEI editions

Frontiers in Computer Science
This study investigates the integration of language models for knowledge extraction (KE) from Italian TEI/XML encoded texts, focusing on Giacomo Leopardi's works.
Cristian Santini
doaj   +1 more source

Does COVID-19 Clinical Status Associate with Outcome Severity? An Unsupervised Machine Learning Approach for Knowledge Extraction. [PDF]

J Pers Med, 2021
Karlafti E, Anagnostis A, Kotzakioulafi E, Vittoraki MC, Eufraimidou A, Kasarjyan K, Eufraimidou K, Dimitriadou G, Kakanis C, Anthopoulos M, Kaiafa G, Savopoulos C, Didangelos T.   +12 more
europepmc   +1 more source

A phase field model incorporating generic and specific prior knowledge applied to road network extraction from VHR satellite images [PDF]

, 2007
Ting Peng, Ian H. Jermyn, V. Prinet, Josiane Zerubia, Bao-Gang Hu   +4 more
openalex   +1 more source

Red blood cells could protect miRNAs from degradation or loss thanks to Argonaute 2 binding

FEBS Open Bio, EarlyView.
The present work investigates the presence and the stability of miRNAs into RBCs, both native and engineered. The observed stability is due to the Ago2 bound resulting in minimal RISC. Indeed, if the miRNA‐Ago2 complex is present, miRNAs are protected from release or degradation and they are biologically active. Thus, RBCs can act as miRNA carriers for
Elena Perla, Faiza Abbas, Luigia Rossi, Mauro Magnani, Sara Biagiotti   +4 more
wiley   +1 more source

Mapping Hsp104 interactions using cross‐linking mass spectrometry

FEBS Open Bio, EarlyView.
This study examines how cross‐linking mass spectrometry can be utilized to analyze ATP‐induced conformational changes in Hsp104 and its interactions with substrates. We developed an analytical pipeline to distinguish between intra‐ and inter‐subunit contacts within the hexameric homo‐oligomer and discovered contacts between Hsp104 and a selected ...
Kinga Westphal, Karolina Michalska, Andrzej Joachimiak, Lukasz A. Joachimiak   +3 more
wiley   +1 more source

Symbolic knowledge extraction from trained neural networks: A sound approach

, 2001
Artur S. d’Avila Garcez, K. Broda, Michael Gabbay   +2 more
openalex   +1 more source

Adopting Graph Traversal Techniques for Context-Driven Value Sets Extraction from Biomedical Knowledge Sources [PDF]

, 2008
Jyotishman Pathak, Guoqian Jiang, Sridhar O. Dwarkanath, J. D. Buntrock, Christopher G. Chute   +4 more
openalex   +1 more source