Results 231 to 240 of about 8,023,305 (265)

Knowledge-graph embeddings for osteoarthritis candidate prediction. [PDF]

NPJ Digit Med
Wang Z, Lu Z, Li M, Zhao P, Zhang C.
europepmc   +1 more source

Dual‐Organelle Secretome Conjugation and Organ‐Uptake Tracking (DuO‐SCOUT) Enables Deep and Sensitive Mapping of the Secreted Proteins

Advanced Science, EarlyView.
A novel dual‐organelle proximity labeling platform, DuO‐SCOUT, decodes the complex landscape of systemic organ‐organ communication by capturing both classical and unconventional secretomes. Application in metabolic models maps the adipose‐to‐brain secretory relay, identifying selective extra‐hypothalamic sites for adipose‐derived factors and expanding ...
Fenglian Yang, Rui Qian, Jiaxing Song, Xingqi Meng, Jin Young Kim, Kwok On Lai, Li Wang, Liang Zhang   +7 more
wiley   +1 more source

Klotho‐Derived Peptide 1 Protects against Acute Kidney Injury by Directly Targeting Mitochondrial ATAD3A

Advanced Science, EarlyView.
This study uncovers that KP1, a Klotho‐derived peptide, protects the kidney against acute kidney injury, a clinical syndrome with high morbidity and mortality. KP1 enters tubular epithelial cells via endocytosis, directly interacts with the mitochondrial ATAD3A/HIGD2A complex, thereby preventing cytochrome c release, and caspases activation, and ...
Xiaoyao Zhang, Shihui Lin, Tianyu Wu, Zhixin Zhang, Hong Zhou, Xue Hong, Youhua Liu   +6 more
wiley   +1 more source

Knowledge graph visualization and bibliometric analysis of research on coronary artery lesions in Kawasaki disease. [PDF]

Medicine (Baltimore)
Huang Y, Zhang Y, Zhang J, Ma X, Zhang Y.   +4 more
europepmc   +1 more source

KGRec: A knowledge graph attention-based model for recommender system. [PDF]

PLoS One
Hoan TD, Hung BT.
europepmc   +1 more source

Knowledge graph visualization and retrospective analysis of genetic research on pediatric cardiomyopathy (2000-2024). [PDF]

Front Cardiovasc Med
Han X, Wang F, Wang G.
europepmc   +1 more source

Structured knowledge representation of the South China Sea: An LLM-based knowledge graph approach. [PDF]

PLoS One
Zhao R, Han Z, Liu H.
europepmc   +1 more source

An agentic AI framework connecting language models to electronic health records and a biomedical knowledge graph for real-world evidence. [PDF]

Front Artif Intell
Bellucci G, Gu W, Rose PW, Baranzini SE.
europepmc   +1 more source