Results 91 to 100 of about 351,050 (219)

Unleashing the Power of Machine Learning in Nanomedicine Formulation Development

open access: yesAdvanced Functional Materials, EarlyView.
A random forest machine learning model is able to make predictions on nanoparticle attributes of different nanomedicines (i.e. lipid nanoparticles, liposomes, or PLGA nanoparticles) based on microfluidic formulation parameters. Machine learning models are based on a database of nanoparticle formulations, and models are able to generate unique solutions
Thomas L. Moore   +7 more
wiley   +1 more source

Expanding Chemical Space of Nucleic Acid Nanoparticles for Tunable Antiviral‐Like Immunomodulatory Responses and Potent Adjuvant Activity

open access: yesAdvanced Functional Materials, EarlyView.
We introduce a nucleic acid nanoparticle (NANP) platform designed to be rrecognized by the human innate immune system in a regulated manner. By changing chemical composition while maintaining constant architectural parameters, we identify key determinants of immunorecognition enabling the rational design of NANPs with tunable immune activation profiles
Martin Panigaj   +21 more
wiley   +1 more source

Review of knowledge graph refinement

open access: yesDianzi Jishu Yingyong, 2018
Knowledge graph is a new knowledge representation method in the mobile Internet era. Knowledge graph refinement is one of the main contents in application of knowledge graph and its main goal are completion and error detection.
Xie Gang
doaj   +1 more source

An All‐Optical Driven Bio‐Photovoltaic Interface for Active Control of Live Cells

open access: yesAdvanced Functional Materials, EarlyView.
Bio‐photovoltaic Interface (BIO‐PV‐I) for live cell manipulation is presented. BIO‐PV‐I can be activated non‐invasively and remotely to control the spatial motility, adhesion, and morphology of cells adhering to it. BIO‐PV‐I uses a patterned light‐induced electric potential in iron‐doped lithium niobate crystals whose light‐driven and reversible nature,
Lisa Miccio   +8 more
wiley   +1 more source

ISA-KGC: Integrated Semantics-Structure Analysis in Knowledge Graph Completion

open access: yesIEEE Access
This paper presents Integrated Semantics-Structure Analysis in Knowledge Graph Completion (ISA-KGC), a new framework for Knowledge Graph Completion (KGC) aimed at addressing the incompleteness of knowledge graphs (KGs).
Xingyu Liu   +5 more
doaj   +1 more source

Exciton Binding Energy Modulation in 2D Perovskites: A Phenomenological Keldysh Framework

open access: yesAdvanced Functional Materials, EarlyView.
The intrinsic screening effects are successfully decoupled from structural distortion by rigorously designing a series of 2D perovskites. This enabled us to demonstrate how the dielectric environment modulates the quasiparticle bandgap and exciton binding energy.
Kitae Kim   +15 more
wiley   +1 more source

Knowledge Embedding with Geospatial Distance Restriction for Geographic Knowledge Graph Completion

open access: yesISPRS International Journal of Geo-Information, 2019
A Geographic Knowledge Graph (GeoKG) links geographic relation triplets into a large-scale semantic network utilizing the semantic of geo-entities and geo-relations.
Peiyuan Qiu   +3 more
doaj   +1 more source

Germanane Quantum Dots Promote Metabolic Reprogramming of Immune Cells Toward Regulatory T Cells and Suppress Inflammation In Vitro and In Vivo

open access: yesAdvanced Functional Materials, EarlyView.
Metabolic changes in immune cells direct the phenotype and function of the host immune system. Smart nanomaterials must target metabolic pathways to direct immune cell fate. This study reports the fabrication and first application of germanane quantum dots (GeHQDs) to modulate inflammation in vitro and in vivo.
Abhay Srivastava   +7 more
wiley   +1 more source

Rational Device Design and Doping‐Controlled Performance in Fast‐Response π‐Ion Gel Transistors

open access: yesAdvanced Functional Materials, EarlyView.
π‐Ion gel transistors (PIGTs) achieve extraordinary transconductance and stability through device configuration optimization, high‐mobility conjugated polymer selection, and hole scavenger doping. The optimized PIGTs maintain performance on flexible substrates, enabling printed, fast‐response, and wearable electronics.
Masato Kato   +10 more
wiley   +1 more source

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