An enhanced framework for knowledge graph embedding based on negative sample analogical reasoning. [PDF]
Li H +5 more
europepmc +1 more source
Enhancing Super‐Resolution Spatial Transcriptomics Data by Transfer Learning
SpotZoomer employs a transfer‐learning‐based strategy to enhance the resolution of Visium data by leveraging available high‐resolution priors. The resulting super‐resolved maps enable sharper delineation of cell boundaries and more precise inference of cell–cell communication patterns that would otherwise remain obscured at native resolution.
Xiaoyu Li, Lihua Zhang, Wenwen Min
wiley +1 more source
GeOKG: geometry-aware knowledge graph embedding for Gene Ontology and genes. [PDF]
Jeong CU, Kim J, Kim D, Sohn KA.
europepmc +1 more source
Polydopamine nanoparticles enable a precise, non‐genetic, and transcranial neuromodulation strategy via near‐infrared photothermal stimulation. By activating TRPV1 channels, this approach specifically enhances hippocampal gamma oscillations, thereby rescuing spatial memory deficits in models of perioperative neurocognitive disorder.
Yan‐Bo Zhou +10 more
wiley +1 more source
Credibility-based knowledge graph embedding for identifying social brand advocates. [PDF]
Abu-Salih B +4 more
europepmc +1 more source
A Literature-Based Knowledge Graph Embedding Method for Identifying Drug Repurposing Opportunities in Rare Diseases. [PDF]
Sosa DN +5 more
europepmc +1 more source
Closing the Empirical Loop: Autonomous AI Agents Conduct End‐to‐end Research With Human Participants
A multi‐agent AI system autonomously executes the complete scientific workflow, from hypothesis to manuscript, across three psychological studies involving 288 participants. The system designs experiments, collects real world data, develops analysis pipelines, and writes manuscripts with theoretical rigor comparable to experienced researchers.
Gabrielle Wehr +6 more
wiley +1 more source
Identifying compound-protein interactions with knowledge graph embedding of perturbation transcriptomics. [PDF]
Ni S +19 more
europepmc +1 more source
The study establishes an immune‐cure (ICu) mouse model based on a TMEMed G422TN‐GBM system that faithfully recapitulates human TMEMed GBM. scRNA‐seq analysis reveals a Csmd3+ microglial subset with innate immune memory (IIM) potential that potently suppresses GBM growth, drives a TME cold‐to‐hot transition, and induces 100% ICu in long‐term survival ...
Hai‐Feng Jiang +12 more
wiley +1 more source
Drug-target interaction prediction using knowledge graph embedding. [PDF]
Li N, Yang Z, Wang J, Lin H.
europepmc +1 more source

