Results 91 to 100 of about 7,514,301 (303)

Cybersecurity knowledge graphs construction and quality assessment

open access: yesComplex & Intelligent Systems, 2023
Cyber-attack activities are complex and ever-changing, posing severe challenges to cybersecurity personnel. Introducing knowledge graphs into the field of cybersecurity helps depict the intricate cybersecurity landscape and provides technical support for
Hongyi Li   +4 more
doaj   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

Semantic Web: Past, Present, and Future [PDF]

open access: yesTransactions on Graph Data and Knowledge
Ever since the vision was formulated, the Semantic Web has inspired many generations of innovations. Semantic technologies have been used to share vast amounts of information on the Web, enhance them with semantics to give them meaning, and enable ...
Scherp, Ansgar   +4 more
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

williamjsdavis/Knowledge-Graphs-for-Seismic-Data-and-Metadata: Update from reviewer comments

open access: yes, 2023
<p>Minor naming changes following with reviewer comments in the associated paper "Knowledge Graphs for Seismic Data and Metadata" (<a href="https://doi.org/10.31223/X5XQ1D">DOI:10.31223/X5XQ1D</a>) by William Davis and ...
William Davis
core   +1 more source

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

open access: yesFEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

Knowledge Graphs on the Web – An Overview

open access: yes, 2020
Knowledge Graphs are an emerging form of knowledge representation. While Google coined the term Knowledge Graph first and promoted it as a means to improve their search results, they are used in many applications today. In a knowledge graph, entities in the real world and/or a business domain (e.g., people, places, or events) are represented as nodes ...
Heist, Nicolas   +3 more
openaire   +2 more sources

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

open access: yesFEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Combining feedback enhancement with knowledge graphs in large language models

open access: yesJournal of King Saud University: Computer and Information Sciences
Large language models (LLMs) for reasoning generation rely on their own already acquired knowledge. However, knowledge in real tasks is updated in real time, and frequent fine-tuning can be cumbersome.
Yulin Zhou, Yongbin Qin, Chuan Lin
doaj   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

open access: yesFEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss   +7 more
wiley   +1 more source

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