Results 51 to 60 of about 238,723 (304)
Path-based knowledge reasoning with textual semantic information for medical knowledge graph completion [PDF]
, 2021 Yinyu Lan +5 more
openalex +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Design Objectives for Evolvable Knowledge Graphs
Complex Systems Informatics and Modeling Quarterly, 2023 Knowledge graphs (KGs) structure knowledge to enable the development of intelligent systems across several application domains. In industrial maintenance, comprehensive knowledge of the factory, machinery, and components is indispensable.
Anna Teern +3 more
doaj +1 more source
Geo-Situation for Modeling Causality of Geo-Events in Knowledge Graphs [PDF]
, 2022 Shirly Stephen +2 more
openalex +1 more source
RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
Applied Sciences, 2023 In the existing medical knowledge graphs, there are problems concerning inadequate knowledge discovery strategies and the use of single sources of medical data.
Menglong Li +5 more
doaj +1 more source
Knowledge graph completion for scholarly knowledge graph
Bulletin of Social Informatics Theory and ApplicationScholarly knowledge graph is a knowledge graph that is used to represent knowledge contained in scientific publication documents. The information we can find in a scientific publication document is as follows: author, institution, name of journal/conference, and research topic. A knowledge graph that has been built is usually still not perfect.
Taufiqurrahman Taufiqurrahman +2 more
openaire +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Cybersecurity knowledge graphs construction and quality assessment
Complex & Intelligent Systems, 2023 Cyber-attack activities are complex and ever-changing, posing severe challenges to cybersecurity personnel. Introducing knowledge graphs into the field of cybersecurity helps depict the intricate cybersecurity landscape and provides technical support for
Hongyi Li +4 more
doaj +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source