Results 81 to 90 of about 17,415,345 (386)
Penerapan Knowledge Management pada Badan Perencanaan Pembangunan Daerah (Bappeda) Kota Pekanbaru [PDF]
Regional Development Planning Agency (Bappeda) of Pekanbaru city is one of the local government institutions accordance with their tasks to help heads of regions in organizing of government in development planning.
Harahap, T. H. (Tuti)+1 more
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Knowledge Management in Knowledge Society
In spite the fact that individuals or even some companies neglect knowledge as one of key resources of contemporary business, knowledge occupies very important position within these successful companies. Dominant opinion of these individuals is that knowledge can’t be measured, and according to that it is not possible to govern with knowledge ...
Strugar, Ivan, Fakleš, Davor
openaire +4 more sources
The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine+10 more
wiley +1 more source
Introduction: Assessment of the citations to scientific researches and journals by invention patents is a way to analyze the relationship between the science and technology.
Shirin Zahedi+2 more
doaj +1 more source
Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma
GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski+19 more
wiley +1 more source
Evaluating a large language model’s ability to answer clinicians’ requests for evidence summaries
Objective: This study investigated the performance of a generative artificial intelligence (AI) tool using GPT-4 in answering clinical questions in comparison with medical librarians’ gold-standard evidence syntheses. Methods: Questions were extracted
Mallory N. Blasingame+6 more
doaj +1 more source
Knowledge Management in Superorganisms [PDF]
JUCS - Journal of Universal Computer Science Volume Nr.
openaire +3 more sources
A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp+13 more
wiley +1 more source
Background: The Department of Health (DoH) at the City of Johannesburg metropolitan municipality in South Africa develops various health awareness campaigns aimed at creating awareness of general health risks within the Johannesburg area.
Karin Eloff, Cornelius J. Niemand
doaj +1 more source
A DIA‐MS‐based proteomics analysis of serum samples from GB patients and healthy controls showed that high levels of IL1R2 and low levels of CRTAC1 and HRG in serum are associated with poor survival outcomes for GB patients. These circulating proteins could serve as biomarkers for the prediction of outcome in patients with GB.
Anne Clavreul+11 more
wiley +1 more source