Results 61 to 70 of about 1,513,338 (266)

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo, Weisi Dai, Jie Mao, Mei Ye, Xingshan Lu, Xiaocui Zhang   +5 more
wiley   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

Krishikosh: A digital repository to disseminate agricultural knowledge

The Indian Journal of Agricultural Sciences, 2018
Krishikosh is a versatile open access digital repository catering to the needs of Indian National Agricultural Research and Education System (NARES) and has architecture of centralized hosting of content but decentralized management.
RAKHEE SHARMA, AMRENDER KUMAR, P S PANDEY, HIMANSHU HIMANSHU, MANSI GUPTA, SANJIV KAPUR, ASHISH SHARMA, A K JAIN   +7 more
doaj   +1 more source

Knowledge Dichotomy and Semantic Knowledge Management [PDF]

, 2006
Today's business is becoming global and knowledge-intensive. This requires business systems capable of knowledge identification, knowledge acquirement, knowledge distribution and knowledge maintenance in terms of universal knowledge understanding. Semantic knowledge management is expected to meet this requirement.
openaire   +2 more sources

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Evaluating a large language model’s ability to answer clinicians’ requests for evidence summaries

Journal of the Medical Library Association
Objective: This study investigated the performance of a generative artificial intelligence (AI) tool using GPT-4 in answering clinical questions in comparison with medical librarians’ gold-standard evidence syntheses. Methods: Questions were extracted
Mallory N. Blasingame, Taneya Y. Koonce, Annette M. Williams, Dario A. Giuse, Jing Su, Poppy A. Krump, Nunzia Bettinsoli Giuse   +6 more
doaj   +1 more source

Knowledge Dissemination based on Social Networks: A Systematic Review [PDF]

کتابداری و اطلاع‌رسانی
Objective: Knowledge is an asset that increases when others share it, and its sharing and dissemination leads to synergy and growth of individual and collective knowledge.
Leila Jabbari, Mohammad Hasanzadeh, Fatemeh Zandian, Atefeh Sharif   +3 more
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Engineering Determinants of Artificial Intelligence Adoption in Indian Healthcare Systems: A Regression-Validated Institutional Readiness Model

مجلة النهرين للعلوم الهندسية
The introduction of Artificial Intelligence (AI) in medical care is becoming an acknowledged challenge in the framework of engineering systems, in which the level of computational readiness, the integration of the infrastructure, the level of user ...
Prateek Singh, Sudipta Das, Justin Babu, Alok Satsangi   +3 more
doaj   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source