Results 201 to 210 of about 42,099 (255)

Livestock Multi‐Omics Integration: A Systematic Framework From Statistical Association to Causal Interpretation

Advanced Science, EarlyView.
A three‐tier livestock multi‐omics framework resolves four typical analytical pitfalls. Moving from statistical association through machine learning preprocessing to triple‐modal causal inference, it converts omics results into genomic selection and gene editing strategies to achieve One Health, underpinned by multi‐omics data, multimodal sequencing ...
Jiying Wen, Zhongyu Wang, Jieping Huang, Fen Li, Ningbo Chen, Yun Ma   +5 more
wiley   +1 more source

An Epigenetic Clock for Accurate Age Prediction in Atlantic Cod Populations for Improved Fisheries Management. [PDF]

Mol Ecol Resour
Anastasiadi D, Kasmi Y, Stransky C, Casas L, Eschbach E, Piferrer F.   +5 more
europepmc   +1 more source

Single‐Cell Profiling Reveals a Protective WNT5A‐ATF3‐FOSB Signaling Axis in Hair Follicle Stem Cells During Androgenetic Alopecia

Advanced Science, EarlyView.
Androgenetic alopecia (AGA) is a common form of hair loss with limited treatment options. Silencing of WNT5A signaling, which is widely known as the trigger of the ncWNT signaling pathway, happens in hair follicle stem cells from balding areas. It leads to downregulation of ATF3 and its target FOSB.
Ruiyu Luo, Ke Fang, Changjiang Zhao, Jiachao Xiong, Yuan Zhu, Mingyang Lu, He Yan, Zihan Li, Baojin Wu, Hua Jiang, Yufei Li   +10 more
wiley   +1 more source

Neuromorphic Devices and Computing for Sensing, Memory, and Control

Advanced Science, EarlyView.
This review introduces neuromorphic devices made from diverse materials. These devices mimic neuronal functions and architectures and, when integrated with artificial or biological computing, can form closed loops with neurons for pressure, optical, acoustic, and biochemical sensing and modulation.
Zhengguang Zhu, Nicholas Schaffer, Xiao Yang   +2 more
wiley   +1 more source

Integrating Creative and Community Health Services into Clinical Workstreams: A Qualitative Case Study from Gloucestershire Integrated Care Board

Hearst J, Chatterjee HJ, Penn F, Gorf H.
europepmc   +1 more source

Research on Precise Detection Methods for the Maturity of <i>Pleurotus ostreatus</i> in Complex Mushroom Cultivation Environments. [PDF]

Sensors (Basel)
Yu J, Luo C, Wei Q, Lu Y, Zheng Y.
europepmc   +1 more source

Chemical Bond‐Orchestrated Energy Depletion to Augment Lung Cancer Chemo‐Immunotherapy

Advanced Science, EarlyView.
This study grafted dichloroacetic acid (DCA) into perylenediimide (PDI) skeleton via ionic or covalent bond to create novel metabolic agent PDIC‐AC and PDIC‐NAC, explicitly elaborated the underlying energy metabolism and therapeutic mechanism, and developed a promising strategy for energy metabolism‐targeting chemo‐immunotherapy by chemical bond ...
Xuejie Zhao, Yuting Liu, Xiao Huang, Liwen Zhao, Chunli Li, Yongwei Huang   +5 more
wiley   +1 more source

A computational validation for the health concept maturity levels questionnaire. [PDF]

Front Psychol
Trognon A, Habibi I, Altakroury H, Mahdar-Recorbet L, Poli A, Servais D, Lambert J, Béjean M, Abraham D.   +8 more
europepmc   +1 more source

A Value-Based Evaluation Framework for Guiding the Adoption and Scale-Up of Cancer Genomics Interventions.

Public Health Genomics
Solís-Díez G, Prats C, Valls-Comamala V, Castellano-García JM, Mias R, Molina-Barceló A, Romeo-Cervera P, Pinto-Carbó M, Retèl VP, van Schaik LF, Van den Bulcke M, Van Valckenborgh E, Maspons R, Alessandrello R.   +13 more
europepmc   +1 more source

The current state of electronic health records across Canada: an environmental scan and interoperability maturity assessment. [PDF]

CMAJ
Kannappan S, Hastings S, Forster A, Dean S, Hollett G, Hagens S, Gheorghiu B, Affleck E, Snyman C, Adams O, Williamson T, Manns B.   +11 more
europepmc   +1 more source