Results 121 to 130 of about 9,418,995 (309)
Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer
Molecular Oncology, EarlyView.Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba +5 more
wiley +1 more source
Map of San Luis Obispo Co. California.
, 1910 Map shows early twentieth century San Luis Obispo County, California township grid, grants, roads, railroads, national forests, ranches, and telephone lines. Includes legend. Scale [1:253,440]
Progressive Map Service
core
USP7 inhibits FOXO1 activity in chronic lymphocytic leukaemia cells enhancing cell survival
Molecular Oncology, EarlyView.CLL cells rely on BCR‐mediated signalling for survival and proliferation in part through suppression of FOXO1. FOXO1 activity is regulated by a plethora of post‐translational modifications including phosphorylation and ubiquitination. We demonstrated that dual inhibition of BCR signalling and the deubiquitinase USP7 activates FOXO1, modulating its ...
Hassan N.B. Almuhanna +8 more
wiley +1 more source
International Journal of Population Data ScienceObjective We aimed to measure the change in proportion of opioid-related overdose deaths attributed to people experiencing homelessness and to compare the opioid-related fatalities between individuals experiencing homelessness and not experiencing ...
Richard Booth +6 more
doaj +1 more source
, 1921 Map shows oil and gas drilling and producing activity; oil and gas fields, pipelines, pump stations, well ownership, railroads, counties, and towns. Includes legend, indexes, and key to geological formations. Insets: "U.S.G.S.
Oil City Map Co.
core
Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids
FEBS Open Bio, EarlyView.Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão +3 more
wiley +1 more source
Clason's Guide to Texas: With Map of Auto Routes
, 1917 Map of the state of Texas and surrounding areas. Individual counties are outlined in green and labeled with roads marked in red and railroads marked in black. Geographic features are marked with relief shown by hachures.
Clason Map Co.
core
Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
Truk Islands [cartographic material] : special strategic map /
, 1962 Ed. 1-AMS. Map of the Chuuk Islands region in the north Pacific Ocean. Relief shown by spot heights.; Compiled "February 1943."; "2-62."; Also available online http://nla.gov.au/nla.map-vn5748169.Title in upper margin: Special strategic map 1:1,000 ...
United States. Army Map Service.
core