Results 111 to 120 of about 9,418,995 (309)

NAPRT loss promotes lung tumor initiation and growth through AKT signaling independently of NAD+ biosynthesis

Molecular Oncology, EarlyView.
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh, Ji Yun Jang, Yoon Jeon, Gi‐Cheon Kim, Hwanho Lee, Jooyoung Lee, Ju‐Hwa Kim, Hakhyun Kim, Minjee Kim, Ho‐Keun Kwon, Ho Lee, Hyun Seok Kim   +11 more
wiley   +1 more source

India and Pakistan 1:250,000 [cartographic material] /

, 1959
Various eds. Topographic map series of India and Pakistan showing populated places, railroads, boundaries and roads. Relief shown by contours and spot heights.
United States. Army Map Service.
core  

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

Manchuria 1:250,000 [cartographic material] /

, 1950
Various eds. "Constructed and molded in 1950 from Manchuria 1:250,000."; Each sheet is named and numbered individually.; Includes glossary and index to adjacent sheets.; Place names in Chinese and Wades Giles romanisation.; Topographic raised relief ...
United States. Army Map Service.
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Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source

“They were just a person who was curious”: Exploring the impact of supportive coaching on the psychosocial well-being of youth transitioning out of homelessness

SSM - Mental Health
Background: Most conversations about the homelessness crisis in high income countries tend to center around the importance of meeting tangible needs like housing; however, there is strong evidence to support that housing is crucial but not sufficient ...
Naomi S. Thulien, Mardi Daley, Alexandra Amiri, Alex Abramovich, Alex Akdikmen, Pruthuvie Chandradhas, Oluwapelumi (Pukky) Fambegbe, Tyler Frederick, Stephen W. Hwang, Nicole Kozloff, Rosane Nisenbaum, Amanda Noble, Giulia Puinean, Marsha Rampersaud, Ruth Rodney, Tadios Tibebu, Rowen K. Stark   +16 more
doaj   +1 more source

Japan road map 1:1,000,000 [cartographic material]/

, 1945
Various eds. Road map series of Japan and Korea showing transportation, water features and populated places. Relief shown by shading and spot heights.; Standard map series designation: [Series] A.M.S.
United States. Army Map Service.
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SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

Truk Islands : special strategic map

, 1945
Scale 1:1,000,000 ; Lambert conformal conic projection. 1 map : color ; 46 x 68 cm. First edition-AMS 1. Prepared under the direction of the Chief of Engineers, U.S. Army ; compiled by the Army Map Service, February 1943. Standard map series designation:
United States. Army Map Service.
core   +1 more source

Indochina 1:100,000 [cartographic material] /

, 1950
Various eds. Map series of Indochina showing roads, railways, canals, international and provincial boundaries, villages, churches, ruins, forest reserves, vegetation and cultivation. Relief shown by contours and spot heights.; "Copied ... from Carte de l'
United States. Army Map Service.
core