Results 91 to 100 of about 5,403,631 (298)
Perceptions of Nursing Students Regarding Evidence-Based Practice [PDF]
, 2009 The purpose of this descriptive quantitative study was to explore the nursing students\u27 perceptions of their attitude and knowledge regarding evidence-based practice (EBP).
Tolentino, Sheleen
core +1 more source
Molecular Oncology, EarlyView.This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad +17 more
wiley +1 more source
Valuing knowledge transfer : a new approach to assessing the broader impact of higher education institutions [PDF]
, 2009 There is considerable policy interest in exploring the overall value of higher education to society and in how higher education can support wider economic growth and development through 'knowledge transfer' from higher education institutions.
Kelly, Ursula +3 more
core
Molecular Oncology, EarlyView.Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande +11 more
wiley +1 more source
MEASURING CONTAGION WITH A BAYESIAN TIME-VARYING COEFFICIENT MODEL [PDF]
We propose to use a time-varying coefficient model to measure contagion. The proposed measure works in the joint presence of heteroskedasticity and omitted variables. It requires knowledge of the source of the crisis but not its timing.
Alessandro Rebucci
core
Rigidity of the 1-Bakry-\'Emery inequality and sets of finite perimeter in RCD spaces
, 2019 This note is dedicated to the study of the asymptotic behaviour of sets of finite perimeter over RCD(K,N) metric measure spaces. Our main result asserts existence of a Euclidean tangent half-space almost everywhere with respect to the perimeter measure ...
Ambrosio, Luigi +2 more
core +1 more source
Molecular Oncology, EarlyView.Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard +12 more
wiley +1 more source
Molecular Oncology, EarlyView.Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard +5 more
wiley +1 more source
How to Measure Procedural Knowledge for Solving Biodiversity and Climate Change Challenges
Education Sciences, 2018 To cope with biodiversity and climate change challenges, Education for Sustainable Development (ESD) needs to emphasize knowledge that considers multiple perspectives.
Lisa Richter-Beuschel +2 more
doaj +1 more source
Survivin and Aurora Kinase A control cell fate decisions during mitosis
Molecular Oncology, EarlyView.Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir +2 more
wiley +1 more source