Results 81 to 90 of about 848,794 (248)

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

Whale Vision: A tool for identifying sperm whales and other cetaceans by their flank or fluke

Ecological Informatics
The Mediterranean sperm whale (Physeter macrocephalus) is classified as endangered, and effective conservation strategies require accurate knowledge of individual whales’ movements and behaviours.
Sammie Fuller, Silvia Maggi, Barbara Mussi, Theodore Kypraios, Michael P. Pound   +4 more
doaj   +1 more source

Referential Transparency of Motivated Public Authorities' Names in Translations

Comparative Legilinguistics, 2019
The paper focuses on adequacy and clarity of motivated public authorities' names in translation of constitutional acts. In order to assess the adequacy level of identification of the authorities' name references in the source legal system, a survey has ...
Iluk Łukasz
doaj   +1 more source

Knowledge of anatomy versus forensic dentistry: An integrative review of the human identification process

, 2021
Com o avanço da ciência forense, tornou-se perceptível o envolvimento da Odontologia Legal no sucesso da identificação humana. Objetivo: Realizar uma revisão integrativa da literatura sobre os principais aspectos anatômicos para a identificação humana em Odontologia Legal.
Veríssimo, Matheus Harllen Gonçalves, Rodrigues, Matheus Andrade, Nóbrega, Waleska Fernanda Souto, Barbosa, Danilo Vieira, Neto, Osires de Medeiros Melo, Dias, Brenno Anderson Santiago, Oliveira, João Paulo Soares de, Santos, Lucas Rodrigues dos, Silva, José Eduardo Galdino da, Almeida , Jhulie Lorrany Mendes de, Ferreira , Myllenna dos Santos, Melo, Priscylla Gabrielly Brasileiro de, Leal, Tauany Maria da Rocha Borges, Silva, Maria Alice Pereira, Silva, Gustavo Correia Basto da   +14 more
openaire   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Multivariable Model for Understanding the Sandpaper Manufacturing Process

Applied System Innovation
In this study, we analyze the production process capability of sandpaper manufacturing, with an emphasis on material removal from the finished product and the identification of manufacturing variables that most influence grinding performance and final ...
Mariana Narváez-Merino, Uziel Mejía-González, Mario Aguilar-Fernández, Misaela Francisco-Márquez, Javier Cruz-Salgado   +4 more
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source