Results 71 to 80 of about 1,523,414 (311)
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Alif 38: Translation and the Production of Knowledge(s) [PDF]
, 2018 The point of departure for this special issue of Alif is that knowledge is \u27produced\u27 rather than \u27discovered,\u27 and that translation is a core mechanism for the production and circulation of all forms of knowledge.
Ghazoul, Ferial J.
core
Interactive Knowledge Co-production and Integration for Healthy Urban Development [PDF]
, 2018 This data is based on paper Shrestha, R., Köckler, H., Flacke, J., Martinez, J., & Van Maarseveen, M. (2017). Interactive knowledge co-production and integration for healthy urban development.
Shrestha, Dr. R. (Faculty of Geo-Information and Earth Observation (ITC), University of Twente), Researcher
core +1 more source
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Actor Roles in an Urban Living Lab: What Can We Learn from Suurpelto, Finland? [PDF]
Technology Innovation Management Review, 2013 There is a growing trend to involve citizens in city development to make urban areas more suitable to their needs and prevent social problems. City centres and neighbourhoods have increasingly been serving as regional living labs, which are ideal ...
Soile Juujärvi, Kaija Pesso
doaj
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Co-production of Knowledge in Action [PDF]
Co-production of actionable knowledge as a development strategy entails working in partnership with different institutions and sharing power so that communities can participate in planning urban futures.
core +1 more source
Knowledge for whose society? Knowledge production, higher education, and federal policy in Canada [PDF]
, 2009 With the dissemination of its Innovation Strategy in 2002, the Canadian government further solidified its commitment to a knowledge-based national competitiveness strategy.
Amy Scott Metcalfe +3 more
core +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source