Results 71 to 80 of about 10,004,617 (373)

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

Knowledge Sharing and the Psychological Contract: Managing Knowledge Workers across Different Stages of Employment [PDF]

open access: yes, 2007
Purpose – An employee’s willingness to share knowledge may be contingent on whether the organization equitably fulfills its reward obligations. This paper seeks to examine how managers and organizations can be vehicles for managing psychological contract
Adya, Monica, O\u27Neill, Bonnie S.
core   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

open access: yesMolecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad   +12 more
wiley   +1 more source

A Conceptual Framework of the Individual Antecedents to Knowledge Sharing- With Empirical Evidence and Managerial Implications

open access: yesSustainable Business and Society in Emerging Economies
Purpose: The increasing importance of knowledge sharing, almost all successful firms deem knowledge sharing and knowledge management as one of the central and strategically most important organizational concerns and allocate huge budgets to the ...
Muhammad Abdul Basit Memon
doaj   +1 more source

Identification of the Constraints and Obstacles to the Creation and Sharing of Knowledge [PDF]

open access: yesمدیریت راهبردی دانش سازمانی, 2019
In today's dynamic environment, knowledge sharing among employees has become a key component of gaining competitive advantage for organizations. Given this, the identification of the effective constraints on knowledge sharing has also become very ...
mohammad solgi, yaser ghasemi
doaj  

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

The factors determining knowledge sharing intention among information professionals in Nigeria

open access: yesRegional Journal of Information and Knowledge Management, 2016
Rationale of Study - Several studies have considered the factors determining the knowledge sharing intention among employees. However, studies focusing on information professionals and factors determining their knowledge sharing intention through a path
Tella Adeyinka
doaj  

Labor market decisions after motherhood: The case of Barcelona 1

open access: yesHeliyon
This article analyses mothers' work decisions and their determinants during the first three years of their children's life, based on data from a survey of 1219 mothers in the Barcelona area during 2020.
Cristina de Gispert   +2 more
doaj   +1 more source

Pengaruh Knowledge Sharing Self-efficacy dan Knowledge Sharing Quality terhadap Supervisor Salesperson Performance [PDF]

open access: yes, 2019
Penelitian ini bertujuan untuk menganalisis pengaruh Self-efficacy dalam berbagi pengetahuan terhadap salesperson performance dengan peran knowledge sharing quality sebagai variabel intervening. Penelitian ini menggunakan metode kuantitatif dengan sampel
Sutanto, C. R. (Cynthia)
core  

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

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