Results 101 to 110 of about 2,103,070 (343)
Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains
FEBS Open Bio, EarlyView.The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth +6 more
wiley +1 more source
An Agent-Based System with Personalization and Intelligent Assistance Services for Facilitating Knowledge Sharing [PDF]
, 2006 The scenario of distributed knowledge in organization, lack of understanding of knowledge sharing benefits and technology inadequacies are the main barriers to knowledge sharing facilitation.
Mohd Sharef, Nurfadhlina
core
Sustainability, 2019 Knowledge sharing behavior based on the cluster innovation network has become the primary measure for enterprises to realize sustainable innovation. In order to promote the proactive knowledge sharing behavior among enterprises in the long term, the ...
Xiaodan Kong, Qi Xu, T. Zhu
semanticscholar +1 more source
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
FEBS Open Bio, EarlyView.Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
Tracking Motor Progression and Device‐Aided Therapy Eligibility in Parkinson's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To characterise the progression of motor symptoms and identify eligibility for device‐aided therapies in Parkinson's disease, using both the 5‐2‐1 criteria and a refined clinical definition, while examining differences across genetic subgroups.
David Ledingham +7 more
wiley +1 more source
BMC NursingBackground In today’s rapidly evolving healthcare environment, nurses’ innovative behaviors are crucial for improving patient care quality and organizational effectiveness.
Nima Gharajeh-Alamdari +3 more
doaj +1 more source
INNOVATIVE WORK BEHAVIOR: EFEK KNOWLEDGE SHARING
Jurnal GeoEkonomiThe research conducted aims to determine the effect of knowledge sharing on innovative work behavior in the workplace. This research method uses descriptive quantitative method. The sample technique in this study used a saturated sample method totaling 95 people who were none other than employees of PT Phapros, Tbk.
Rindyani, Wahyu, Mansyur, Anwar
openaire +2 more sources
Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon +12 more
wiley +1 more source
Why Would Anyone Like To Share His Knowledge? [PDF]
, 2001 Why do workers within organizations, or organizations in a network share information and knowledge? This question reverses the logic in some of the knowledge management literature, which addresses impediments and problems in information and knowledge ...
Homburg, V.M.F. (Vincent) +1 more
core
Effect of Local Population Uncertainty on Cooperation in Bacteria
, 2017 Bacteria populations rely on mechanisms such as quorum sensing to coordinate complex tasks that cannot be achieved by a single bacterium. Quorum sensing is used to measure the local bacteria population density, and it controls cooperation by ensuring ...
Eckford, Andrew W. +4 more
core +1 more source