Results 81 to 90 of about 2,103,070 (343)

Initiating private-collective innovation: The fragility of knowledge sharing [PDF]

, 2010
Incentives to innovate are a central element of innovation theory. In the private-investment model, innovators privately fund innovation and then use intellectual property protection mechanisms to appropriate returns from these investments.
Arrow, Baldwin, Bellemare, Bergquist, Bessen, Boldrin, Brandts, Brandts, Broothaerts, Cabrera, Camerer, Casadesus-Masanell, Charness, Dasgupta, de Vries, Demsetz, di Norcia, Dufwenberg, Elster, Engelmann, Falk, Faraj, Fehr, Fehr, Feldman, Fischbacher, Foss, Foss, Franke, Garud, Georg von Krogh, Grant, Hargrave, Harhoff, Henkel, Hertel, Holmstrom, Hope, Huber, Jefferson, Jeppesen, Kim, Kogut, Kogut, Kogut, Kuk, Lakhani, Lakhani, Leonard-Barton, Lerner, Lerner, Meloso, Michailova, Montmarquette, Moody, Moon, Nonaka, Nonnecke, Olson, Osterloh, Osterloh, O’Mahony, Rabin, Raymond, Roberts, Ryan, Selten, Shah, Simon Gächter, Smith, Stefan Haefliger, Stephan, Stuermer, Szulanski, Takeishi, Teece, Teece, Useem, von Hippel, von Hippel, von Hippel, von Krogh, Wasko, Weber, Weber, Weber, Zwick   +86 more
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

TRUST AND INNOVATIVE WORK BEHAVIOR:

Journal of Management Small and Medium Enterprises (SME's)
The creative industry is an economic sector focused on creating and distributing products related to creativity, ideas, and innovation. In order to be competitive, the creative industry sector needs innovation.
Nur Auliyah, Muhammad Ali Fikri, Made Galih Wisnu Wardana   +2 more
doaj   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

DAMPAK PERSEPSI DUKUNGAN ORGANISASI DAN KARATERISTIK PEKERJAAN TERHADAP KNOWLEDGE SHARING: PERAN ORGANIZATIONAL CITIZENSHIP BEHAVIOR SEBAGAI VARABEL MEDIASI

Jurnal Manajemen Universitas Bung Hatta, 2020
Organizational citizenship behavior has been recognized as an important variable for every organization both in academicians and practitioners. The purpose of this study is to investigate the role of organizatinal citizenship behavior as mediator on the ...
Tri Sukma, Fitri Handayani, Sefnedi Sefnedi   +2 more
doaj   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Knowledge sharing and social technology acceptance model: promoting local events and festivals through facebook [PDF]

, 2013
This study examines Facebook page “events” as a medium for promoting special events to consumers. It proposes a Social Technology Acceptance Model, an extension of the Technology Acceptance Model, to examine the influence of Trust, Strength of ...
Lee, Woojin, Paris, Cody Morris
core   +1 more source

Evolutionary Game Analysis on Knowledge-Sharing Behavior in the Construction Supply Chain

Sustainability, 2019
With the increasingly fierce global competition, supply chain members have to collaborate to respond to constant changes. Efficient knowledge sharing is the basis for the collaborative operation of the supply chain. Combined with evolutionary game theory,
Chanchan Hao, Q. Du, Youdan Huang, Long Shao, Yunqing Yan   +4 more
semanticscholar   +1 more source

Knowledge sharing in organizations: Roles of beliefs, training, and perceived organizational support

Knowledge Management & E-Learning: An International Journal, 2018
The main objective of this study was to test the effects of two types of beliefs about knowledge sharing, i.e., individual and collective, on the intention and behavior of knowledge sharing.
Delio Ignacio Castaneda, William Fernando Durán   +1 more
doaj