Results 71 to 80 of about 1,325,670 (296)

Organizational changes, trust and information sharing: an empirical study [PDF]

, 2019
Purpose While there is relatively plenty of evidence for the positive impact of communication on the perceptions of organizational change, how organizational changes affect information sharing is relatively unknown.
AHMAD, FARHAN, Huvila, Isto
core   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Knowledge sharing among inventors: Some historical perspectives [PDF]

, 2011
This chapter documents instances from past centuries where inventors freely shared knowledge of their innovations with other inventors. It is widely believed that such knowledge sharing is a recent development, as in Open Source Software.
Bessen, James, Nuvolari, Alessandro
core  

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

The Relationship Between Employee Perceptions of the Employment Game and Their Perceptions of Cooperative Knowledge Behavior in High Tech Firms [PDF]

, 2000
The relationship between knowledge sharing and organizational performance for high technology start-up companies is not well understood. Using game theory and the concept of competitive advantage through human resource management, I examine employee ...
Rogers, Edward William
core   +1 more source

Knowledge sharing and social technology acceptance model: promoting local events and festivals through facebook [PDF]

, 2013
This study examines Facebook page “events” as a medium for promoting special events to consumers. It proposes a Social Technology Acceptance Model, an extension of the Technology Acceptance Model, to examine the influence of Trust, Strength of ...
Lee, Woojin, Paris, Cody Morris
core   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Assessing the Effectiveness of Assistance in Capacity Development [PDF]

, 2009
{Excerpt} Feedback is a circular causal process whereby some portion of a system’s output is returned to the input to control the dynamic behavior of the system. In organizations, feedback is the process of sharing observations, concerns, and suggestions
Serrat, Olivier
core   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

Investigating the Status of Knowledge Sharing and Its Relationship with Innovative Work Behavior of Employees (Case Study: Manufacturing Company) [PDF]

مدیریت راهبردی دانش سازمانی, 2022
The innovative behavior of employees in the role of the main students of the organization, especially in manufacturing companies, is essentially subject to the behavior of their knowledge in the workplace. This is at the individual level depending on the
Farzaneh Reyhani Shukkat Abad, Rezvan Hosseingholizadeh, Alireza Khorakiyan   +2 more
doaj