Results 51 to 60 of about 11,475,056 (247)

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

The Effects of Personal and Environmental Factors on the Process of Knowledge Sharing with the Role of Education Moderator [PDF]

open access: yesبازیابی دانش و نظام‌های معنایی, 2018
Aim: The subject of knowledge sharing is one of the important challenges in knowledge management. According to the Bandura theory, personal factors, environmental factors, and behavior are in reciprocal relations with each other.
Mostafa Jafari   +2 more
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Determinants of knowledge-sharing intention and knowledge-sharing behavior in a public organization

open access: yesKnowledge Management & E-Learning: An International Journal, 2016
The purpose of this paper is to examine the factors that affect the knowledge-sharing intention and knowledge-sharing behavior in a public sector organization.
Delio Ignacio Castaneda   +2 more
doaj  

WHAT TO TEACH IN THE INTRODUCTORY CIS COURSE? [PDF]

open access: yesIssues in Information Systems, 2011
This research investigates the roles of sense of self-worth, in-role behavior, and organizational citizenship behavior in supporting individuals’ knowledge sharing behavior, by incorporating a motivational aspect into the theory of reasoned action ...
Jeanne Baugh, Paul Kovacs
doaj  

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

Impact of Emotional Intelligence on Knowledge Sharing and Knowledge Hiding Behavior [PDF]

open access: yes, 2022
During the last few decades, researchers have proven that controlling and sharing employee knowledge is critical for effective organizational transformation, innovation, and competitive advantage.
Toker, Alpaslan, Mahmood, Nadra
core  

Knowledge-Sharing in an Online Community of Health-care Professionals [PDF]

open access: yes, 2007
Purpose – The purposes of this study are twofold: (1) to examine the types of activity that nurses undertake on an online community of practice (APN-l) as well as the types of knowledge that nurses share with one another and (2) to examine the factors ...
Hara , Noriko   +6 more
core   +2 more sources

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

open access: yesFEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

open access: yesMolecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic   +15 more
wiley   +1 more source

Home - About - Disclaimer - Privacy