Results 41 to 50 of about 11,475,056 (247)

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

A Study on Knowledge Sharing Mechanism among Enterprise Research and Development Personnel [PDF]

, 2007
How to promote knowledge sharing is the core of knowledge management to create value for the organization. The paper explored knowledge sharing mechanism among enterprise research and development personnel from three level factors: individual, group and ...
Sun, Lili, Zhang, Shuhua
core  

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Understand knowledge workers in using KMS for knowledge sharing [PDF]

, 2012
This study contributes to enrich our understanding of knowledge workers' behavior in continuing knowledge sharing through Knowledge Management System (KMS).
Che Hussin, Ab. Razak, Assegaff, Setiawan, Mohamed Dahlan, Halina   +2 more
core  

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

The theory of planned behavior and knowledge sharing: A systematic review and meta-analytic structural equation modelling. [PDF]

, 2018
The theory of planned behavior (TPB) is the most frequently used model in knowledge sharing. However, the empirical results are inconclusive on whether TPB can provide reasonable prediction of knowledge sharing behavior (KSB).
Nham, PT, Nguyen, TM, Nguyen, Tuyet-Mai, Hoang, VN, Nham, Phong Tuan, Hoang, Viet Ngu   +5 more
core   +1 more source

The Enactment of Knowledge Sharing: The Roles of Psychological Availability and Team Psychological Safety Climate

Frontiers in Psychology, 2020
Scholars have made great efforts to investigate the antecedents of knowledge sharing. In the current study, we applied the proactive motivation model (Parker et al., 2010) to propose a theoretical model to advance this research line and examined the ...
Jing Qian, Wei Zhang, Yi Qu, Bin Wang, Meng Chen   +4 more
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

The mediating effect of knowledge sharing in the relationship between factors affecting knowledge sharing and reflective thinking: the case of English literature students during the COVID-19 crisis

Research and Practice in Technology Enhanced Learning, 2022
The COVID-19 pandemic has had serious implications on educational systems worldwide and, hence, online courses have been organized. It is expected that the use of online learning in higher education promote knowledge sharing among students and the ...
Majid Farahian, Farshad Parhamnia, Nasser Maleki   +2 more
doaj   +1 more source