Results 51 to 60 of about 20,443,898 (250)

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Knowledge translation in Africa: are the structures in place?

open access: yesImplementation Science Communications, 2020
Background Contextualised evidence to generate local solutions on the progressive path to universal health coverage is essential. However, this evidence must be translated into action.
James Avoka Asamani   +1 more
doaj   +1 more source

Transdisciplinarity ‘Meets’ Power Structures: Challenges and Experiences of a Capacity Building Project on Transdisciplinarity

open access: yesASEAS - Austrian Journal of South-East Asian Studies, 2020
The aim of the paper is to discuss and to reflect on the experiences and challenges encountered during the North-South capacity building project on transdisciplinarity, KNOTS (Fostering Multi-Lateral Knowledge Networks of Transdisciplinary Studies to ...
Petra Dannecker
doaj   +1 more source

Discursive structures and power relations in Covid-19 knowledge production

open access: yesHumanities & Social Sciences Communications, 2021
This article critically examines the discourse around the Covid-19 pandemic to investigate the widespread polarisation evident in social media debates. The model of epidemic psychology holds that initial adverse reactions to a new disease spread through ...
Mario Bisiada
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Employee green behavior: mapping knowledge structures and future directions

open access: yesCogent Business & Management
This study aims to provide an empirical analysis of publications in employee green behavior based on journal articles by revealing publication trends, impactful authors, leading journals, and the most influential articles.
Winda Widyanty   +9 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

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