Results 51 to 60 of about 4,007,505 (289)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Knowledge translation in Africa: are the structures in place?

Implementation Science Communications, 2020
Background Contextualised evidence to generate local solutions on the progressive path to universal health coverage is essential. However, this evidence must be translated into action.
James Avoka Asamani, Juliet Nabyonga-Orem   +1 more
doaj   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Discursive structures and power relations in Covid-19 knowledge production

Humanities & Social Sciences Communications, 2021
This article critically examines the discourse around the Covid-19 pandemic to investigate the widespread polarisation evident in social media debates. The model of epidemic psychology holds that initial adverse reactions to a new disease spread through ...
Mario Bisiada
doaj   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Two-photon absorption in microcavities for optical autocorrelation and sampling [PDF]

, 2003
We have designed novel semiconductor microcavity structures for the enhancement of the two-photon absorption (TPA) photocurrent. We report a TPA autocorrelation technique for short optical pulses that uses the microcavity structure instead of a second ...
Barry, Liam P., Bradley, Ann Louise, Donegan, John Francis, Folliot, H., Hill, G., Krug, T., Lynch, Michael, Roberts, J.S.   +7 more
core   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Employee green behavior: mapping knowledge structures and future directions

Cogent Business & Management
This study aims to provide an empirical analysis of publications in employee green behavior based on journal articles by revealing publication trends, impactful authors, leading journals, and the most influential articles.
Winda Widyanty, Dian Primanita Oktasari, Setyo Riyanto, Dewi Nusraningrum, Sih Damayanti, Sik Sumaedi, I. Gede Mahatma Yuda Bakti, Anggini Dinaseviani, Prita Prasetya, Mochammad Fahlevi   +9 more
doaj   +1 more source

Transdisciplinarity ‘Meets’ Power Structures: Challenges and Experiences of a Capacity Building Project on Transdisciplinarity

ASEAS - Austrian Journal of South-East Asian Studies, 2020
The aim of the paper is to discuss and to reflect on the experiences and challenges encountered during the North-South capacity building project on transdisciplinarity, KNOTS (Fostering Multi-Lateral Knowledge Networks of Transdisciplinary Studies to ...
Petra Dannecker
doaj   +1 more source

Metrics for ranking ontologies [PDF]

, 2006
Representing knowledge using domain ontologies has shown to be a useful mechanism and format for managing and exchanging information. Due to the difficulty and cost of building ontologies, a number of ontology libraries and search engines are coming to ...
Alani, Harith, Brewster, Christopher
core   +3 more sources