Results 71 to 80 of about 20,443,898 (250)

Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers

open access: yesFEBS Letters, EarlyView.
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui   +4 more
wiley   +1 more source

A Knowledge Structures Perspective on the Scholarship of Teaching & Learning

open access: yesInternational Journal for the Scholarship of Teaching and Learning, 2009
The application of concept mapping to university teaching has revealed the significance of knowledge structures in the process of student learning. The method highlights the negative influence of linearity in promoting an environment where non-learning ...
Ian Kinchin
doaj   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

open access: yesFEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil   +3 more
wiley   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

台灣原住民族知識組織架構建構方法之探討 A Study on the Method of Constructing Taiwan Aboriginal Knowledge Organization Structure [PDF]

open access: yesJiàoyù zīliào yǔ túshūguǎn xué, 2010
近年來,原住民族知識組織架構愈來愈受各界的關注與重視,然而由於過去原住民知識大多皆以口傳為主,顯少有文字記載,故原住民族知識組織架構建構之不完整性是可想而知的。 為因應此劃時代之趨勢與需求,本研究旨在提出一套建構「台灣原住民族知識組織架構」之方法與步驟:透過對各種「知識組織系統」類型特色與呈現方式的分析,本研究認為「分類架構」應是目前較適用於呈現原住民族領域知識的知識組織系統;再藉由「領域分析」方法的探討,整合出台灣原住民族領域知識分析之整體流程;並根據現有之原住民族知識組織架構及其建構之相關研究 ...
Hsueh-Hua Chen
doaj  

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

open access: yesFEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Polytomous Knowledge Structures Based on Entail Relations

open access: yesMathematics
In knowledge structure theory (KST), an individual’s knowledge state represents the items that the individual can completely solve. Based on the differences in individuals’ latent cognitive competence, polytomous knowledge states can be used to partially
Zhaorong He
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Knowledge management framework (kmf) based on layers

open access: yesVisión Electrónica, 2016
Research in the eld of Knowledge Management (KM) has grown in accumulation and importance in both the academic and business worlds. However, it has not properly established how and when a KM initiative should be implemented.
Juan C. Guevara B.   +2 more
doaj  

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

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