Results 81 to 90 of about 20,443,898 (250)

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

open access: yesMolecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen   +19 more
wiley   +1 more source

Conservazione e sicurezza strutturale nel patrimonio novecentesco: spunti di riflessione per un indirizzo normativo /

open access: yesRestauro Archeologico
The verification of structural safety and the consolidation of 20th-century architecture in ‘mixed’ or reinforced concrete structures are complex issues in the current debate, partly because the regulatory instruments governing structural restoration ...
Adalgisa Donatelli
doaj   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso   +5 more
wiley   +1 more source

Knowledge Administration Within Modern Business Structures [PDF]

open access: yesOvidius University Annals: Economic Sciences Series
The research aims to develop a conceptual framework for analyzing the relationship of determination between the dimensions of the organization that characterize the elements of intellectual capital and each of the stages of the organization, taking ...
Anca Madalina Bogdan   +2 more
doaj  

The relation between knowledge management strategies and organization structures [PDF]

open access: yesمطالعات مدیریت بهبود و تحول, 2009
In this paper we exploring that how we can choose the best structure for an organization by using the concept of knowledge management also we examine the above issue in the an organization with organic structure (Leaming organization) and with stable ...
mir ali seyed naghavi
doaj  

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

open access: yesMolecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba   +5 more
wiley   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

open access: yesFEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão   +3 more
wiley   +1 more source

Frost-salt Testing Non-air Entrained High-Performance Fly-ash Concrete. Part I: Relations Liquid uptake - Internal Cracking – Scaling

open access: yesNordic Concrete Research
The surface scaling of low CO2-emission High Performance Concretes (HPC) was studied in freeze/thaw performance tests with a 3 mm layer of 3% NaCl on the surface to investigate whether such concretes can be made frost durable without air entrainment ...
Asadi Iman   +3 more
doaj   +1 more source

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