Results 81 to 90 of about 3,241,412 (295)

Revisiting knowledge transfer for training object class detectors

open access: yes, 2018
We propose to revisit knowledge transfer for training object detectors on target classes from weakly supervised training images, helped by a set of source classes with bounding-box annotations.
Ferrari, Vittorio   +2 more
core   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

Knowledge Transfer, Innovation and Growth [PDF]

open access: yes
Recent empirical work has examined the extent to which national and international spillovers affect the functioning of a firm. Foreign direct investment and trade have been shown to serve as channels for the mediation of knowledge spillovers.
Damijan, Jože P., Kostevc, Crt
core  

Impact of a senior research thesis on students' perceptions of scientific inquiry in distinct student populations

open access: yesFEBS Open Bio, EarlyView.
This study addressed how a senior research thesis is perceived by undergraduate students. It assessed students' perception of research skills, epistemological beliefs, and career goals in Biochemistry (science) and BDC (science‐business) students. Completing a thesis improved confidence in research skills, resilience, scientific identity, closed gender‐
Celeste Suart   +4 more
wiley   +1 more source

CAMKK1 in Obesity and Type 2 Diabetes Mellitus: Evidence of Interaction With Appetite‐Regulating, Metabolic and Inflammatory Factors

open access: yesEndocrinology, Diabetes & Metabolism
Introduction Calcium/calmodulin‐dependent protein kinase kinase 1 (CAMKK1) regulates energy homeostasis through AMP‐activated protein kinase (AMPK). CAMKK1 has been implicated in appetite and satiety regulation; however, its role in obesity or type 2 ...
Livio Tarchi   +11 more
doaj   +1 more source

Effective knowledge transfer to SMEs [PDF]

open access: yes
EIM examined to what extent small and medium-sized enterprises may be stimulated to absorb more know-how in respect of for instance new process technology to use that know-how for in-company business process upgrading.
Arnoud Muizer, Richard Kerste
core  

Interactive transfer guide: sharing knowledge from the ESRALE project [PDF]

open access: yes, 2016
The Interactive Transfer Guide (ITG) is an expert resource that summarises and points users to where they can find the full details of the distinctive knowledge developed as part of the ESRALE project, including the key outputs and lessons learned. It is
Zubrzycki, Tanya
core  

Navigating new norms: a systematic review of factors for the development of effective digital tools in higher education

open access: yesFEBS Open Bio, EarlyView.
What factors make for an effective digital learning tool in Higher Education? This systematic review identifies elements of a digital tool that published examples reveal to be features of an engaging and impactful digital tool. A systematic literature search yielded 25 research papers for analysis.
Akmal Arzeman   +4 more
wiley   +1 more source

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