Results 31 to 40 of about 1,800,671 (290)

Addressing the quality and scope of paediatric primary care in South Africa: evaluating contextual impacts of the introduction of the Practical Approach to Care Kit for children (PACK Child)

BMC Health Services Research, 2020
Background Despite significant reductions in mortality, preventable and treatable conditions remain leading causes of death and illness in children in South Africa.
Jamie Murdoch, Robyn Curran, Ruth Cornick, Sandy Picken, Max Bachmann, Eric Bateman, Makhosazana Lungile Simelane, Lara Fairall   +7 more
doaj   +1 more source

Comparison of research framing preferences and information use of state legislators and advocates involved in cancer control, United States, 2012–2013 [PDF]

, 2017
INTRODUCTION: Evidence-based policy plays an important role in prevention of cancer and other chronic diseases. The needs of actors involved in policy decision-making should inform knowledge translation strategies.
Brownson, Ross C, Dodson, Elizabeth A, Morshed, Alexandra B, Tabak, Rachel G   +3 more
core   +2 more sources

Efficacy of antimalarial herbal medicines used by communities in malaria affected regions globally: a protocol for systematic review and evidence and gap map

BMJ Open, 2023
Introduction With the rising resistance to artemisinin-based combination treatments, there is a need to hasten the discovery and development of newer antimalarial agents. Herbal medicines are key for the development of novel drugs.
Nakalembe Loyce, Robert Apunyo, Alison Annet Kinengyere, Moses Ocan, Ekwaro A Obuku, Kevin Ouma Ojiambo   +5 more
doaj   +1 more source

An Approach for Chinese-Japanese Named Entity Equivalents Extraction Using Inductive Learning and Hanzi-Kanji Mapping Table [PDF]

, 2017
Named Entity Translation Equivalents extraction plays a critical role in machine translation (MT) and cross language information retrieval (CLIR). Traditional methods are often based on large-scale parallel or comparable corpora.
Araki, Kenji, Chen, Yufeng, Ru, Kuang, Xu, JinAn, Zhang, Yujie   +4 more
core   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Towards a taxonomy of behavior change techniques for promoting shared decision making

Implementation Science, 2020
Background There is little information about the functions and behavior change techniques (BCTs) needed to implement shared decision making (SDM) in clinical practice.
Titilayo Tatiana Agbadjé, Hélène Elidor, Milena Sia Perin, Rhéda Adekpedjou, France Légaré   +4 more
doaj   +1 more source

Theory-based approach to developing an implementation plan to support the adoption of a patient decision aid for Down syndrome prenatal screening

Implementation Science, 2021
Background Our team has developed a decision aid to help pregnant women and their partners make informed decisions about Down syndrome prenatal screening. However, the decision aid is not yet widely available in Quebec’s prenatal care pathways. Objective
Titilayo Tatiana Agbadjé, Matthew Menear, Marie-Pierre Gagnon, France Légaré   +3 more
doaj   +1 more source

TermEval: an automatic metric for evaluating terminology translation in MT [PDF]

, 2019
Terminology translation plays a crucial role in domain-specific machine translation (MT). Preservation of domain-knowledge from source to target is arguably the most concerning factor for the customers in translation industry, especially for critical ...
Haque, Rejwanul, Hasanuzzaman, Mohammed, Way, Andy   +2 more
core  

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Comparative effectiveness and safety of pharmacological and non-pharmacological interventions for insomnia: an overview of reviews

Systematic Reviews, 2019
Background This review aimed to assess the existing evidence regarding the clinical effectiveness and safety of pharmacological and non-pharmacological interventions in adults with insomnia and identify where research or policy development is needed ...
Patricia Rios, Roberta Cardoso, Deanna Morra, Vera Nincic, Zahra Goodarzi, Bechara Farah, Sharada Harricharan, Charles M. Morin, Judith Leech, Sharon E. Straus, Andrea C. Tricco   +10 more
doaj   +1 more source